Evidence map›Paper›PMID 33333419›Full record

ArticleThe International journal on drug policy2021

Selectivity and sensitivity of urine fentanyl test strips to detect fentanyl analogues in illicit drugs.

Marianne Skov-Skov Bergh, Åse Marit Leere Øiestad, Michael H Baumann, Inger Lise Bogen

Open access · hybridAbstract read
In one paragraph

Article in The International journal on drug policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
6.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 87 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Marianne Skov-Skov BerghSection for Drug Abuse Research, Department of Forensic Sciences, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway; Department of Chemistry, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway. Electronic address: Marianne.Skov-Skov.Bergh@ous-hf.no.
Åse Marit Leere ØiestadSection for Drug Abuse Research, Department of Forensic Sciences, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Michael H BaumannDesigner Drug Research Unit, Intramural Research Program, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Baltimore, MD, USA.
Inger Lise BogenSection for Drug Abuse Research, Department of Forensic Sciences, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway; Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Oslo University Hospital · NONational Institute on Drug Abuse · US

Funding

Studies on MDMA and Related CompoundsZIADA000523 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI BAUMANN, MICHAEL · 2009 to 2025
$16.4M
Preclinical medication development for stimulant use disorderZIADA000522 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI BAUMANN, MICHAEL · 2009 to 2025
$8.9M
Intramural NIH HHS ZIA DA000522
6 · The paper itself

Abstract

backgroundUrine fentanyl test strips have been employed to check street drugs for fentanyl and fentanyl analogue contamination, but there is limited evidence for the applicability of fentanyl strips for this purpose. We examined the ability of four commercially-available fentanyl test strips to detect fentanyl and a range of fentanyl analogues currently on the recreational drug market.

methodsFour brands of fentanyl test strips (Rapid Response, One Step, Nal van Minden, and Rapid Self Test) were examined using single-component drug solutions containing fentanyl, 28 fentanyl analogues, four non-fentanyl synthetic opioids, or eight traditional drugs of abuse. The effect of co-presence of heroin or ascorbic acid on test results was also examined.

resultsAll test strips detected fentanyl as well as 21-24 of the 28 fentanyl analogues tested. One of the test strip brands gave false positive results in the presence of ascorbic acid.

conclusionsFentanyl test strips successfully detected the majority of fentanyl analogues tested. Drug solutions for testing should not be overly dilute, since the test results are highly concentration dependent. Fentanyl test strips have utility as a harm reduction tool, but they are no panacea for overdose since certain fentanyl analogues are not detected.

Indexed as

Drug OverdoseIllicit DrugsOpioid-Related DisordersAnalgesics, OpioidFentanylHumansAnalgesics, OpioidFentanylIllicit DrugsAscorbic acidFentanyl analoguesFentanyl test stripsHeroinOverdose preventionSynthetic opioids

Identifiers

PMID33333419
PMCPMC13622938
OpenAlexW3113261358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.