Evidence map›Paper›PMID 33332997›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Preclinical Development of Virulence-attenuated

Elisa Ramos-Sevillano, Giuseppe Ercoli, Philip Felgner, Rafael Ramiro de Assis, Rie Nakajima, David Goldblatt, Robert S Heyderman, Stephen B Gordon, Daniela M Ferreira, Jeremy S Brown

Open access · greenAbstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

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  5. Identification ofJournal of proteome research · 2025
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  8. Naturally acquired adaptive immunity toClinical & translational immunology · 2024
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  11. Non-capsular based immunization approaches to preventFrontiers in cellular and infection microbiology · 2022
    Review
  12. Maintained partial protection againstClinical & translational immunology · 2022
    Article
  13. Article
  14. Review
  15. Vaccination With the CommensalFrontiers in immunology · 2021
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Elisa Ramos-SevillanoUniversity College London London, United Kingdom.ORCID 0000-0003-0803-2755
Giuseppe ErcoliUniversity College London London, United Kingdom.
Philip FelgnerUniversity of California Irvine Irvine, California.
Rafael Ramiro de AssisUniversity of California Irvine Irvine, California.
Rie NakajimaUniversity of California Irvine Irvine, California.
David GoldblattNIHR Biomedical Research Centre London, United Kingdom.
Robert S HeydermanUniversity College London London, United Kingdom.ORCID 0000-0003-4573-449X
Stephen B GordonMalawi-Liverpool-Wellcome Trust Clinical Research Programme Blantyre, Malawi and.
Daniela M FerreiraLiverpool School of Tropical Medicine Liverpool, United Kingdom.
Jeremy S BrownUniversity College London London, United Kingdom.
The London College · GBUniversity of California, Irvine · USLiverpool School of Tropical Medicine · GBUCL Biomedical Research Centre · GBUniversity of Liverpool · GB

Funding

Medical Research Council MR/N02687X/1Medical Research Council MR/R001871/1Medical Research Council MR/T016329/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAntibodies, BacterialFemaleHumansMaleMiddle AgedPneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeVaccines, AttenuatedVirulenceAntibodies, BacterialPneumococcal VaccinesVaccines, Attenuated

Identifiers

PMID33332997
PMCPMC8048742
OpenAlexW3110754037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.