Evidence map›Paper›PMID 33332751›Full record

ArticleESC heart failure2021

Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2.

Cristina Ciuca, Marianna Fabi, Daniela Di Luca, Fabio Niro, Chiara Ghizzi, Andrea Donti, Anna Balducci, Alessandro Rocca, Chiara Zarbo, Gaetano Domenico Gargiulo and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Fulminant Myocarditis with SARS-CoV-2 Infection: A Narrative Review from the Case Studies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
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  8. Giant Coronary Aneurysm in an Infant with Multisystem Inflammatory Syndrome.Heart views : the official journal of the Gulf Heart Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Cristina CiucaPediatric Cardiology and Cardiac Surgery Unit, University of Bologna, S. Orsola Hospital, Bologna, Italy.
Marianna FabiDepartment of Pediatrics, University of Bologna, S. Orsola Hospital, Bologna, Italy.ORCID 0000-0002-2727-3506
Daniela Di LucaDepartment of Anesthesiology, University of Bologna, S. Orsola Hospital, Bologna, Italy.
Fabio NiroDepartment of Radiology, University of Bologna, S. Orsola Hospital, Bologna, Italy.
Chiara GhizziDepartment of Pediatrics, Maggiore Hospital, Bologna, Italy.
Andrea DontiPediatric Cardiology and Cardiac Surgery Unit, University of Bologna, S. Orsola Hospital, Bologna, Italy.
Anna BalducciPediatric Cardiology and Cardiac Surgery Unit, University of Bologna, S. Orsola Hospital, Bologna, Italy.
Alessandro RoccaDepartment of Pediatrics, University of Bologna, S. Orsola Hospital, Bologna, Italy.
Chiara ZarboDepartment of Pediatrics, University of Bologna, S. Orsola Hospital, Bologna, Italy.
Gaetano Domenico GargiuloPediatric Cardiology and Cardiac Surgery Unit, University of Bologna, S. Orsola Hospital, Bologna, Italy.
Marcello LanariDepartment of Pediatrics, University of Bologna, S. Orsola Hospital, Bologna, Italy.
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITOspedale Maggiore Carlo Alberto Pizzardi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 6-year-old African boy with multi-viral infection including parvovirus B19 and severe acute respiratory syndrome coronavirus 2 was admitted for persistent fever associated with respiratory distress and myocarditis complicated by cardiogenic shock needing ventilatory and inotropic support. Coronary aneurysms were also documented in the acute phase. Blood tests were suggestive of macrophage activation syndrome. He was treated with intravenous immunoglobulins, aspirin, diuretics, dexamethasone, hydroxychloroquine, and prophylactic low molecular weight heparin. Normalization of cardiac performance and coronary diameters was noticed within the first days. Cardiac magnetic resonance imaging, performed 20 days after the hospitalization, evidenced mild myocardial interstitial oedema with no focal necrosis, suggesting a mechanism of cardiac stunning related to cytokines storm rather than direct viral injury of cardiomyocytes.

Indexed as

Acute DiseaseChildCoronary AneurysmCOVID-19EchocardiographyHumansMagnetic Resonance ImagingMaleMyocarditisTomography, X-Ray ComputedChildrenCoronary aneurysmsCOVID-19MyocarditisShock

Identifiers

PMID33332751
PMCPMC7835580
OpenAlexW3111601404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.