Evidence map›Paper›PMID 33332626›Full record

ArticleMedical physics2021

Technical Note: kV-independent coronary calcium scoring: A phantom evaluation of score accuracy and potential radiation dose reduction.

Shengzhen Tao, Emily Sheedy, Michael Bruesewitz, Nikkole Weber, Kyle Williams, Ahmed Halaweish, Bernhard Schmidt, Eric Williamson, Cynthia McCollough, Shuai Leng

Abstract read
In one paragraph

Article in Medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shengzhen TaoDepartment of Radiology, Mayo Clinic, Jacksonville, FL, USA.
Emily SheedyDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Michael BruesewitzDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Nikkole WeberDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Kyle WilliamsDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Ahmed HalaweishSiemens Healthineers, 40 Liberty Blvd., Malvern, PA, USA.
Bernhard SchmidtSiemens Healthineers, Siemensstraße 1, Forchheim, 91301, Germany.
Eric WilliamsonDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Cynthia McColloughDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Shuai LengDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.

Funding

Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient managementR01EB028590 · NIBIB · MAYO CLINIC ROCHESTER · PI LENG, SHUAI, MCCOLLOUGH, CYNTHIA H · 2020 to 2023
$2.6M
NIBIB NIH HHS R01 EB028590
6 · The paper itself

Abstract

purposeTo determine the accuracy of CT number and calcium score of a kV-independent technique based on an artificial 120 kV reconstruction, and its potential to reduce radiation dose.

methodsAnthropomorphic chest phantoms were scanned on a third-generation dual-source CT system equipped with the artificial 120 kV reconstruction. First, a phantom module containing a 20-mm diameter hydroxyapatite (HA) insert was scanned inside the chest phantoms at different tube potentials (70-140 kV) to evaluate calcium CT number accuracy. Next, three small HA inserts (diameter/length = 5 mm) were inserted into a pork steak and scanned inside the phantoms to evaluate calcium score accuracy at different kVs. Finally, the same setup was scanned using automatic exposure control (AEC) at 120 kV, and then with automatic kV selection (auto-kV). Phantoms were also scanned at 120 kV using a size-dependent mA chart. CT numbers of soft tissue and calcium were measured from different kV images. Calcium score of each small HA insert was measured using commercial software.

resultsThe CT number difference from 120 kV was small with tube potentials from 90 to 140 kV for both soft tissue and calcium (maximal difference of 4/5 HU, respectively). Consistent calcium scores were obtained from images of different kVs compared to 120 kV, with a relative difference <8%. Auto-kV provided a 25-34% dose reduction compared to AEC alone.

conclusionA kV-independent calcium scoring technique can produce artificial 120 kV images with consistent soft tissue and calcium CT numbers compared to standard 120 kV examinations. When coupled with auto-kV, this technique can reduce radiation by 25-34% compared to that with AEC alone, while providing consistent calcium scores as that of standard 120 kV examinations.

Indexed as

CalciumCoronary Artery DiseaseDrug TaperingHumansPhantoms, ImagingRadiation DosageTomography, X-Ray ComputedCalciumAgatston scoreautomatic exposure controlcalcium scorecardiac CTdose reduction

Identifiers

PMID33332626
PMCPMC8042601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.