Evidence map›Paper›PMID 33332386›Full record

Trial reportPloS one2020

Prevalence and risk factors of disability and anxiety in a retrospective cohort of 432 survivors of Coronavirus Disease-2019 (Covid-19) from China.

Siyi Zhu, Qiang Gao, Lin Yang, Yonghong Yang, Wenguang Xia, Xiguo Cai, Yanping Hui, Di Zhu, Yanyan Zhang, Guiqing Zhang and 16 more

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Improving Pathways to Care for Ethnic Minority Communities.Advances in experimental medicine and biology · 2024
    Review
  7. Observational
  8. Article
  9. Review
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 14 institutions in 3 countries.

Siyi ZhuRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-8213-7622
Qiang GaoRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Lin YangRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Yonghong YangRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Wenguang XiaHubei Hospital of Integrated Traditional Chinese and Western Medicine, Wuhan, Hubei, China.
Xiguo CaiHenan Provincial People's Hospital, Zhengzhou, Henan, China.
Yanping HuiThe Second Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xian, Shanxi, China.
Di ZhuZhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China.
Yanyan ZhangQilu Hospital of Shandong University, Jinan, Shandong, China.
Guiqing ZhangThe First Affiliated Hospital, School of Medicine, Shihezi University, Xinjiang, China.
Shuang WuThe Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Yiliang WangChongqing Three Gorges Central Hospital, Chongqing, China.
Zhiqiang ZhouInner Mongolia Autonomous Region Baotou Central Hospital, Baotou, China.
Hongfei LiuGeneral Hospital of General Bureau of Agricultural Reclamation of Heilongjiang Province, Harbin, China.
Changjie ZhangThe Second Xiangya Hospital of Central South University, Changsha, China.
Bo ZhangNanchong Central Hospital, Nanchong, Sichuan, China.
Jianrong YangGarze People's Hospital, Garze Tibetan Autonomous Prefecture, Sichuan, China.
Mei FengDepartment of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Zhong NiDepartment of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Baoyu ChenRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Chunping DuRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Hongchen HeRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Yun QuRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Quan WeiRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Chengqi HeRehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Jan D ReinhardtInstitute for Disaster Management and Reconstruction of Sichuan University and Hong Kong Polytechnic University, Sichuan University, Chengdu, China.
Sichuan University · CNHong Kong Polytechnic University · HKBaotou Central Hospital · CNCentral South University · CNChongqing Three Gorges Central Hospital · CNGuiyang Medical University · CNHeilongjiang Academy of Land Reclamation Sciences · CNHenan Provincial People's Hospital · CNNanchong Central Hospital · CNQilu Hospital of Shandong University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CNShihezi University · CNTibet Autonomous Region People's Hospital · CNZhejiang Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate the prevalence of disability and anxiety in Covid-19 survivors at discharge from hospital and analyze relative risk by exposures.

designMulti-center retrospective cohort study.

settingTwenty-eight hospitals located in eight provinces of China.

methodsA total of 432 survivors with laboratory-confirmed SARS CoV-2 infection participated in this study. At discharge, we assessed instrumental activities of daily living (IADL) with Lawton's IADL scale, dependence in activities of daily living (ADL) with the Barthel Index, and anxiety with Zung's self-reported anxiety scale. Exposures included comorbidity, smoking, setting (Hubei vs. others), disease severity, symptoms, and length of hospital stay. Other risk factors considered were age, gender, and ethnicity (Han vs. Tibetan).

resultsPrevalence of at least one IADL problem was 36.81% (95% CI: 32.39-41.46). ADL dependence was present in 16.44% (95% CI: 13.23-20.23) and 28.70% (95% CI: 24.63-33.15) were screened positive for clinical anxiety. Adjusted risk ratio (RR) of IADL limitations (RR 2.48, 95% CI: 1.80-3.40), ADL dependence (RR 2.07, 95% CI 1.15-3.76), and probable clinical anxiety (RR 2.53, 95% CI 1.69-3.79) were consistently elevated in survivors with severe Covid-19. Age was an additional independent risk factor for IADL limitations and ADL dependence; and setting (Hubei) for IADL limitations and anxiety. Tibetan ethnicity was a protective factor for anxiety but a risk factor for IADL limitations.

conclusionA significant proportion of Covid-19 survivors had disability and anxiety at discharge from hospital. Health systems need to be prepared for an additional burden resulting from rehabilitation needs of Covid-19 survivors.

Indexed as

Anxiety DisordersCOVID-19Persons with DisabilitiesSARS-CoV-2SurvivorsActivities of Daily LivingAdultAgedAge FactorsChinaFemaleHumansMaleMiddle AgedPrevalenceRetrospective Studies

Identifiers

PMID33332386
PMCPMC7746260
OpenAlexW3113300247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.