Evidence map›Paper›PMID 33332372›Full record

ArticlePloS one2020

Barriers and enablers to the implementation of protocol-based imaging in pancreatic cancer: A qualitative study using the theoretical domains framework.

Ashika D Maharaj, Sue M Evans, John R Zalcberg, Liane J Ioannou, Marnie Graco, Daniel Croagh, Charles H C Pilgrim, Theresa Dodson, David Goldstein, Jennifer Philip and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 1 country.

Ashika D MaharajSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.ORCID 0000-0002-4725-613X
Sue M EvansSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
John R ZalcbergSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Liane J IoannouSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Marnie GracoAlfred Health, Melbourne, Victoria, Australia.
Daniel CroaghMonash Health, Clayton, Victoria, Australia.
Charles H C PilgrimAlfred Health, Melbourne, Victoria, Australia.
Theresa DodsonMonash Health, Clayton, Victoria, Australia.
David GoldsteinPrince of Wales Clinical School, University of New South Wales, Randwick, New South Wales, Australia.
Jennifer PhilipSt Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
James G KenchRoyal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Neil D MerrettSchool of Medicine, Western Sydney University, Penrith South, New South Wales, Australia.ORCID 0000-0002-8370-0293
Rachel E NealeQIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
Kate WhiteSydney Nursing School, University of Sydney, Sydney, New South Wales, Australia.
Peter EvansPeninsula Health, Frankston, Victoria, Australia.
Trevor LeongUniversity of Melbourne, Melbourne, Victoria, Australia.
Sally E GreenSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Alfred Health · AUMonash University · AUMonash Health · AUThe University of Melbourne · AUCancer Council Victoria · AUPeninsula Health · AUQIMR Berghofer Medical Research Institute · AURoyal Prince Alfred Hospital · AUThe University of Sydney · AUUNSW Sydney · AUWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate pre-operative imaging plays a vital role in patient selection for surgery and in allocating stage-appropriate therapies to patients diagnosed with pancreatic cancer (PC). This study aims to: (1) understand the current diagnosis and staging practices for PC; and (2) explore the factors (barriers and enablers) that influence the use of a pancreatic protocol computed tomography (PPCT) or magnetic resonance imaging (MRI) to confirm diagnosis and/or accurately stage PC.

methodsSemi-structured interviews were conducted with radiologists, surgeons, gastroenterologists, medical and radiation oncologists from the states of New South Wales (NSW) and Victoria, Australia. Interviews were conducted either in person or via video conferencing. All interviews were recorded, transcribed verbatim, de-identified and data were thematically coded according to the 12 domains explored within the Theoretical Domains Framework (TDF). Common belief statements were generated to compare the variation between participant responses.

findingsIn total, 21 clinicians (5 radiologists, 10 surgeons, 2 gastroenterologists, 4 medical and radiation oncologists) were interviewed over a four-month-period. Belief statements relevant to the TDF domains were generated. Across the 11 relevant domains, 20 themes and 30 specific beliefs were identified. All TDF domains, with the exception of social influences were identified by participants as relevant to protocol-based imaging using either a PPCT or MRI, with the domains of knowledge, skills and environmental context and resources being offered by most participants as being relevant in influencing their decisions.

conclusionsTo maximise outcomes and personalise therapy it is imperative that diagnosis and staging investigations using the most appropriate imaging modalities are conducted in a timely, efficient and effective manner. The results provide an understanding of specialists' opinion and behaviour in relation to a PPCT or MRI and should be used to inform the design of future interventions to improve compliance with this practice.

Indexed as

Magnetic Resonance ImagingPrecision MedicineTomography, X-Ray ComputedFemaleHumansMaleNeoplasm StagingPancreatic NeoplasmsQualitative Research

Identifiers

PMID33332372
PMCPMC7746147
OpenAlexW3110998152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.