ArticleJAMA network open2020
Incidence and Characteristics of Nonfatal Opioid Overdose Among Youths Aged 11 to 24 Years by Sex.
Article in JAMA network open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Opioid Misuse and Suicide-Related Outcomes Among Adolescents and Young Adults: A Systematic Review.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Pooled it
- Nonfatal Drug Overdose in a National Sample of Adolescents by Intent and Substance, Medicaid 2016-2020.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Digital mental health tools for use by individuals in opioid use recovery: An academic scoping and commercial review.PLOS digital health · 2026Article
- Medication and Acute Care Use in Young Adults With Opioid Use Subject to Medicaid Prescription Caps.JAMA health forum · 2026Article
- Applying the Consolidated Framework for Implementation Research (CFIR) to understand college health administrator perceptions on adopting and implementing opioid overdose education and naloxone distribution (OEND) programs among universities nationally.Harm reduction journal · 2026Article
- Gender differences in opioid and stimulant poisoning in the central region of iran: a cross-sectional study.Scientific reports · 2025Article
- Two doses of Qβ virus like particle vaccines elicit protective antibodies against heroin and fentanyl.NPJ vaccines · 2025Article
- Understanding the impact of the gut microbiome on opioid use disorder: Pathways, mechanisms, and treatment insights.Microbial biotechnology · 2024Review
- Overdose Experiences Among a Sample of Women in Jail with Opioid Use Disorder.Substance use & misuse · 2024Article
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- Article
- Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Sex-specific inflammatory and white matter effects of prenatal opioid exposure: a pilot study.Pediatric research · 2023Article
- Nonmedical Prescription Drug Use Among Female Adolescents: The Relative Influence of Maternal Factors, Social Norms, and Perceptions of Risk and Availability.Drugs (Abingdon, England) · 2023Article
- Article
- Current and emerging pharmacotherapies for opioid dependence treatments in adults: a comprehensive update.Expert opinion on pharmacotherapy · 2022Review
- An Immunconjugate Vaccine Alters Distribution and Reduces the Antinociceptive, Behavioral and Physiological Effects of Fentanyl in Male and Female Rats.Pharmaceutics · 2022Article
- Longitudinal trajectories of prescription opioid misuse in adolescents.Drug and alcohol dependence · 2022Article
- Increasing preference for fentanyl among a cohort of people who use opioids in Vancouver, Canada, 2017-2018.Substance abuse · 2022Article
- Opioid use disorder: a neglected human immunodeficiency virus risk in American adolescents.AIDS (London, England) · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Importance: Opioid-related overdose has substantially increased among adolescents and young adults in recent years. How overdose differs by age and sex among youths and the factors associated with overdose by sex remain poorly described. Objective: To compare the sociodemographic and clinical characteristics of female and male youths who have experienced a nonfatal opioid overdose (NFOD) and compare the incidence of NFOD by sex. Design, Setting, and Participants: This retrospective cohort study used data on US individuals aged 11 to 24 years with a diagnosis of NFOD from the IBM MarketScan Commercial Database from January 1, 2006, through December 31, 2017. Exposure: Sex. Main Outcomes and Measures: The primary outcome was NFOD stratified by sex; covariates included sociodemographic and clinical characteristics. Results: Among 20 312 youths aged 11 to 24 years who had a history of NFOD and met study eligibility criteria, the median age was 20 years (interquartile range, 18-22 years; mean [SD] age, 20.0 [2.9] years) and 56.7% were male. Compared with male youths, female youths had a higher baseline prevalence of mood or anxiety disorder (65.5% vs 51.9%, P < .001), trauma and stress-related disorders (16.4% vs 10.1%, P < .001), and history of suicide attempt or self-harm (14.6% vs 9.9%, P < .001). Male youths had a higher prevalence of opioid use disorder (44.7% vs 29.2%, P < .001), cannabis use disorder (18.3% vs 11.3%, P < .001), and alcohol use disorder (20.3% vs 14.4%, P < .001). The incidence rate ratio of NFODs in females vs males was greater than 1 for ages 11 to 16 years and was less than or equal to 1 after age 17 years. Conclusions and Relevance: This cohort study found differences between female and male youths in sociodemographic and clinical characteristics and incidence of NFOD. Although female and male youths who experience overdose appear to have different risk factors, many of these risk factors may be amenable to early detection through screening and intervention.
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