Evidence map›Paper›PMID 33331461›Full record

Observational studyArquivos brasileiros de cardiologia2021

Evaluation of 1-Year Follow-up of Patients Included in the Registry of Clinical Practice in Patients at High Cardiovascular Risk (REACT).

Pedro Gabriel Melo de Barros E Silva, Otavio Berwanger, Dalton Bertolim Precoma, Margaret Assad Cavalcante, José Fernando Vilela-Martin, Estêvão Lanna Figueiredo, Renato Delascio Lopes, Luiz Carlos Bodanese, Jorge Ilha Guimarães, Jadelson Pinheiro de Andrade and 5 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Arquivos brasileiros de cardiologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  6. Chronic Coronary Syndrome In Brazil: We Need To Know More.Arquivos brasileiros de cardiologia · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Pedro Gabriel Melo de Barros E SilvaInstituto de Pesquisa HCor, Sao Paulo, SP - Brasil.ORCID 0000-0003-1940-4470
Otavio BerwangerHospital Israelita Albert Einstein, Sao Paulo, SP - Brasil.
Dalton Bertolim PrecomaPontificia Universidade Católica do Paraná - Escola de Medicina, Curitiba, PR - Brasil.ORCID 0000-0002-1187-8690
Margaret Assad CavalcanteUniversidade do Oeste Paulista (Unoeste), Presidente Prudente, SP - Brasil.
José Fernando Vilela-MartinFaculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, SP - Brasil.ORCID 0000-0001-6960-2825
Estêvão Lanna FigueiredoHospital Lifecenter, Belo Horizonte, MG - Brasil.ORCID 0000-0001-5420-2482
Renato Delascio LopesDuke University Hospital, Durham, North Carolina - EUA.
Luiz Carlos BodaneseHospital São Lucas, Porto Alegre, RS - Brasil.
Jorge Ilha GuimarãesSociedade Brasileira de Cardiologia, Rio de Janeiro, RJ - Brasil.
Jadelson Pinheiro de AndradeHospital da Bahia, Salvador, BA - Brasil.
Angelo Amato Vincenzo de PaolaUniversidade Federal de São Paulo Escola Paulista de Medicina, São Paulo, SP - Brasil.
Marcus Vinicius Bolivar MalachiasFaculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG - Brasil.ORCID 0000-0002-8171-3920
Luiz Alberto Piva E MattosRede D'or de Hospitais, São Paulo, SP - Brasil.
Fernando BacalUniversidade de São Paulo Faculdade de Medicina Hospital das Clínicas Instituto do Coração, São Paulo, SP - Brasil.
Oscar Pereira DutraInstituto de Cardiologia - Fundação Universitária de Cardiologia do Rio Grande do Sul, Porto Alegre, RS - Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn clinical practice, there is evidence of failure to prescribe evidence-based therapies for patients at high cardiovascular risk. However, in Brazil, data on 1-year outcomes of these patients remain insufficient.

objectivesTo describe the use of evidence-based therapies and the occurrence of major cardiovascular outcomes and their major predictors in a 12-month follow-up of a Brazilian multicenter registry of patients at high cardiovascular risk.

methodsThis prospective observational study documented the outpatient clinical practice of managing patients over 45 years of age and of high cardiovascular risk in both primary and secondary prevention. Patients were followed-up for 1 year, and the prescription of evidence-based therapies and the occurrence of major cardiovascular events (myocardial infarction, stroke, cardiac arrest, and cardiovascular death) were assessed. P-values < 0.05 were considered statistically significant.

resultsFrom July 2010 to August 2014, a total of 5076 individuals were enrolled in 48 centers, 91% of the 4975 eligible patients were followed-up in cardiology centers, and 68.6% were in secondary prevention. At 1 year, the concomitant use of antiplatelet agents, statins, and angiotensin-converting enzyme inhibitors reduced from 28.3% to 24.2% (p < 0.001). Major cardiovascular event rate was 5.46%, and the identified predictors were age, patients in secondary prevention, and diabetic nephropathy.

conclusionsIn this large national registry of patients at high cardiovascular risk, risk predictors similar to those of international registries were identified, but medical prescription adherence to evidence-based therapies was inferior and significantly worsened at 1 year. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0).

Indexed as

Cardiovascular DiseasesBrazilFollow-Up StudiesHeart Disease Risk FactorsHumansRegistriesRisk Factors

Identifiers

PMID33331461
PMCPMC8159499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.