Evidence map›Paper›PMID 33331416›Full record

ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2020

Modeling of post-traumatic epilepsy and experimental research aimed at its prevention.

A C Mosini, M L Calió, M L Foresti, R P S Valeriano, E Garzon, L E Mello

Abstract read
In one paragraph

Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A C MosiniDepartamento de Fisiologia, Universidade Federal de São Paulo, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-7005-4192
M L CalióDepartamento de Fisiologia, Universidade Federal de São Paulo, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-4367-2283
M L ForestiInstituto D'Or de Pesquisa e Ensino, Rio de Janeiro, RJ, Brasil.ORCID http://orcid.org/0000-0002-1950-5215
R P S ValerianoDivisão de Clínica Neurológica, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-2942-5366
E GarzonDivisão de Clínica Neurológica, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-6274-9207
L E MelloDepartamento de Fisiologia, Universidade Federal de São Paulo, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-6969-1108

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on the prevention of post-traumatic epilepsy (PTE) has seen remarkable advances regarding its physiopathology in recent years. From the search for biomarkers that might be used to indicate individual susceptibility to the development of new animal models and the investigation of new drugs, a great deal of knowledge has been amassed. Various groups have concentrated efforts in generating new animal models of traumatic brain injury (TBI) in an attempt to provide the means to further produce knowledge on the subject. Here we forward the hypothesis that restricting the search of biomarkers and of new drugs to prevent PTE by using only a limited set of TBI models might hamper the understanding of this relevant and yet not preventable medical condition.

Indexed as

Brain Injuries, TraumaticDisease Models, AnimalEpilepsy, Post-TraumaticAnimalsBiomarkersBiomarkers

Identifiers

PMID33331416
PMCPMC7747873

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.