ArticleJournal of biomedical optics2020
Imaging of enthesitis by an LED-based photoacoustic system.
Article in Journal of biomedical optics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Volumetric ultrasound and photoacoustic imaging of inflammatory arthritis in human finger joints via robotic arm powered arc scans.Biomedical optics express · 2025Article
- Molecular imaging using (nano)probes: cutting-edge developments and clinical challenges in diagnostics.RSC advances · 2025Review
- Cost-Effective Photoacoustic Imaging Using High-Power Light-Emitting Diodes Driven by an Avalanche Oscillator.Sensors (Basel, Switzerland) · 2025Article
- Application of multispectral optoacoustic tomography for lower limb musculoskeletal sports injuries in adults.Photoacoustics · 2024Article
- U-Net enhanced real-time LED-based photoacoustic imaging.Journal of biophotonics · 2024Article
- Multispectral Optoacoustic Tomography Enables In Vivo Anatomical and Functional Assessment of Human Tendons.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- An Automatic 3-D Ultrasound and Photoacoustic Combined Imaging System for Human Inflammatory Arthritis.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- Photoacoustic clinical applications: Musculoskeletal and abdominal imaging.Zeitschrift fur medizinische Physik · 2023Review
- Longitudinal volumetric assessment of inflammatory arthritis via photoacoustic imaging and Doppler ultrasound imaging.Photoacoustics · 2023Article
- Photoacoustic Imaging of COVID-19 Vaccine Site Inflammation of Autoimmune Disease Patients.Sensors (Basel, Switzerland) · 2023Article
- LED-based photoacoustic imaging for preoperative visualization of lymphatic vessels in patients with secondary limb lymphedema.Photoacoustics · 2023Article
- Optoacoustic Imaging in Inflammation.Biomedicines · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
significanceOne key pathological characteristic of seronegative spondyloarthropathy (SpA) is inflammation at the insertion of tendons and ligaments into the bone (enthesitis).
aimWe explore the potential of the emerging photoacoustic (PA) imaging in diagnosis of SpA and review its feasibility in detecting SpA-associated Achilles tendon enthesitis. APPROACH: A light-emitting diode (LED)-based PA and ultrasound combined system was employed. The PA images, both along the long and the short axes of each Achilles tendon insertion region, were acquired at 850-nm wavelength, which is sensitive in depicting increased blood volume (i.e., hyperemia). To assess the hyperemia indicating enthesis inflammation, two parameters were quantified in the imaged tendons, including the average intensity and the density of the color pixels in the pseudo-color PA images. Ten SpA patients, all of which met Assessment of SpA International Society (ASAS) criteria for SpA and were found to have Achilles enthesitis by clinical exam according to a board-certified rheumatologist, were included in the study.
resultsThe PA and Doppler ultrasound imaging of Achilles enthesitis resulting from these 10 SpA patients were compared to those from 10 healthy volunteers, leading to statistically significant differences (p < 0.05) in the applied t-tests.
conclusionsThis preliminary clinical study suggests that the LED-based PA imaging holds a promise for sensitive and objective assessment of SpA enthesitis in an outpatient setting of the rheumatology clinic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.