Evidence map›Paper›PMID 33331066›Full record

ArticleInternational wound journal2021

The impact of surgical site infection on hospitalisation, treatment costs, and health-related quality of life after vascular surgery.

Joshua Phillip Totty, Joe William Edward Moss, Erin Barker, Stuart James Mealing, John William Posnett, Ian Clifford Chetter, George Edward Smith

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International wound journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 6 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 6 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Acute Bacterial Skin and Skin Structure Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
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  13. Surgical Site Infection in Coronary Artery Bypass: Observational Study.International journal of nursing practice · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Joshua Phillip TottyAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.ORCID https://orcid.org/0000-0002-0063-1414
Joe William Edward MossYork Health Economics Consortium, University of York, York, UK.
Erin BarkerYork Health Economics Consortium, University of York, York, UK.
Stuart James MealingYork Health Economics Consortium, University of York, York, UK.
John William PosnettIndependent health economics consultant, York, UK.
Ian Clifford ChetterAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
George Edward SmithAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Leeds and York Partnership NHS Foundation Trust · GBHull York Medical School · GBCastle Hill Hospital · GBOldham Council · GB

Funding

Essity
6 · The paper itself

Abstract

Surgical site infections (SSI) substantially increase costs for healthcare providers because of additional treatments and extended patient recovery. The objective of this study was to assess the cost and health-related quality of life impact of SSI, from the perspective of a large teaching hospital in England. Data were available for 144 participants undergoing clean or clean-contaminated vascular surgery. SSI development, length of hospital stay, readmission, and antibiotic use were recorded over a 30-day period. Patient-reported EQ-5D scores were obtained at baseline, day 7 and day 30. Linear regressions were used to control for confounding variables. A mean SSI-associated length of stay of 9.72 days resulted in an additional cost of £3776 per patient (including a mean antibiotic cost of £532). Adjusting for age, smoking status, and procedure type, SSI was associated with a 92% increase in length of stay (P < 0.001). The adjusted episode cost was £3040. SSI reduced patient utility between baseline and day 30 by 0.156 (P = 0.236). Readmission rates were higher with SSI (P = 0.017), and the rate to return to work within 90 days was lower. Therefore, strategies to reduce the risk of surgical site infection for high-risk vascular patients should be investigated.

Indexed as

Health Care CostsQuality of LifeSurgical Wound InfectionEnglandHumansLength of StayMaleRisk FactorsVascular Surgical Procedurescosthealth-related quality of lifeinfectionregressionvascular surgery

Identifiers

PMID33331066
PMCPMC8243999
OpenAlexW3116290275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.