Evidence map›Paper›PMID 33330999›Full record

Trial reportJournal of the European Academy of Dermatology and Venereology : JEADV2021

Neurokinin-1 receptor antagonist tradipitant has mixed effects on itch in atopic dermatitis: results from EPIONE, a randomized clinical trial.

S E Welsh, C Xiao, A R Kaden, J L Brzezynski, M A Mohrman, J Wang, S P Smieszek, B Przychodzen, S Ständer, C Polymeropoulos and 2 more

Open access · hybridAbstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in Journal of the European Academy of Dermatology and Venereology : JEADV, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. The Future of Atopic Dermatitis Treatment.Advances in experimental medicine and biology · 2024
    Review
  9. Review
  10. Challenges and Future Trends in Atopic Dermatitis.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. The Implications of Pruritogens in the Pathogenesis of Atopic Dermatitis.International journal of molecular sciences · 2021
    Review
  18. Review
  19. Rosacea Treatment: Review and Update.Dermatology and therapy · 2021
    Review
  20. Itch in Atopic Dermatitis - What Is New?Frontiers in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

S E WelshVanda Pharmaceuticals Inc., Washington, DC, USA.
C XiaoVanda Pharmaceuticals Inc., Washington, DC, USA.
A R KadenVanda Pharmaceuticals Inc., Washington, DC, USA.
J L BrzezynskiVanda Pharmaceuticals Inc., Washington, DC, USA.
M A MohrmanVanda Pharmaceuticals Inc., Washington, DC, USA.
J WangVanda Pharmaceuticals Inc., Washington, DC, USA.
S P SmieszekVanda Pharmaceuticals Inc., Washington, DC, USA.ORCID https://orcid.org/0000-0002-8006-0454
B PrzychodzenVanda Pharmaceuticals Inc., Washington, DC, USA.
S StänderDepartment of Dermatology, Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
C PolymeropoulosVanda Pharmaceuticals Inc., Washington, DC, USA.
G BirznieksVanda Pharmaceuticals Inc., Washington, DC, USA.
M H PolymeropoulosVanda Pharmaceuticals Inc., Washington, DC, USA.
Vanda Pharmaceuticals (United States) · USUniversity Hospital Münster · DE

Funding

Vanda Pharmaceuticals
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dermatitis, AtopicEczemaHumansNeurokinin-1 Receptor AntagonistsPruritusNeurokinin-1 Receptor Antagonists

Identifiers

PMID33330999
PMCPMC8248080
OpenAlexW3118198095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.