Evidence map›Paper›PMID 33330989›Full record

ArticleMolecular microbiology2021

σ

Nina Pennetzdorfer, Thomas Höfler, Martina Wölflingseder, Sarah Tutz, Stefan Schild, Joachim Reidl

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Non-O1/Non-O139Microorganisms · 2024
    Review
  3. Article
  4. Article
  5. Frontiers in medicine · 2023
    Review
  6. σMolecular microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nina PennetzdorferInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Thomas HöflerInstitute of Molecular Biosciences, University of Graz, Graz, Austria.ORCID 0000-0001-7486-5582
Martina WölflingsederInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Sarah TutzInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Stefan SchildInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Joachim ReidlInstitute of Molecular Biosciences, University of Graz, Graz, Austria.ORCID 0000-0001-5798-9524
University of Graz · AT

Funding

Austrian Science Fund FWF P 29405
6 · The paper itself

Abstract

Bile resistance is essential for enteric pathogens, as exemplified by Vibrio cholerae, the causative agent of cholera. The outer membrane porin OmpU confers bacterial survival and colonization advantages in the presence of host-derived antimicrobial peptides as well as bile. Expression of ompU is controlled by the virulence regulator ToxR. rpoE knockouts are accompanied by suppressor mutations causing ompU downregulation. Therefore, OmpU constitutes an intersection of the ToxR regulon and the σ

Indexed as

Adhesins, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsDNA-Binding ProteinsGene DeletionGene Expression Regulation, BacterialPorinsPromoter Regions, GeneticSigma FactorTranscription FactorsVibrio choleraeAdhesins, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsDNA-Binding ProteinsOmpU protein, Vibrio choleraePorinsSigma Factorsporulation-specific sigma factorstoxR protein, Vibrio choleraeTranscription FactorsOmpURpoEstress responseToxRtranscriptional regulation and Vibrio cholerae

Identifiers

PMID33330989
PMCPMC8359247
OpenAlexW3113332851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.