Evidence map›Paper›PMID 33330938›Full record

ReviewThe Journal of infectious diseases2021

Current Capabilities of Gut Microbiome-Based Diagnostics and the Promise of Clinical Application.

Gregory L Damhorst, Max W Adelman, Michael H Woodworth, Colleen S Kraft

Abstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  7. Article
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  10. Article
  11. A novel method for precise endoscopic sampling of duodenal microbiota.Frontiers in cellular and infection microbiology · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
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  17. Endogenous ethanol production in health and disease.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  18. Article
  19. Review
  20. Isolation, identification, and significance of salivaryFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gregory L DamhorstDepartment of Medicine, Division of Infectious Diseases, Emory School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-2237-1713
Max W AdelmanDepartment of Medicine, Division of Infectious Diseases, Emory School of Medicine, Atlanta, Georgia, USA.
Michael H WoodworthDepartment of Medicine, Division of Infectious Diseases, Emory School of Medicine, Atlanta, Georgia, USA.
Colleen S KraftDepartment of Medicine, Division of Infectious Diseases, Emory School of Medicine, Atlanta, Georgia, USA.

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
Temporal dynamics of MDRO eradication after FMTK23AI144036 · NIAID · EMORY UNIVERSITY · PI WOODWORTH, MICHAEL HOLMES · 2019 to 2023
$957k
NIAID NIH HHS K23 AI144036NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

There is increasing evidence for the importance of the gut microbiome in human health and disease. Traditional and modern technologies - from cell culture to next generation sequencing - have facilitated these advances in knowledge. Each of the tools employed in measuring the microbiome exhibits unique capabilities that may be leveraged for clinical diagnostics. However, much still needs to be done to standardize the language and metrics by which a microbiome is characterized. Here we review the capabilities of gut microbiome-based diagnostics, review selected examples, and discuss the outlook towards clinical application.

Indexed as

Clinical Laboratory TechniquesComputational BiologyGastrointestinal MicrobiomeHigh-Throughput Nucleotide SequencingHumansMetagenomics16S amplicon sequencingdiagnosticsmetagenomic sequencingmicrobiome

Identifiers

PMID33330938
PMCPMC8206793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.