Evidence map›Paper›PMID 33330850›Full record

ReviewRadiology. Imaging cancer2020

Development of Multispectral Optoacoustic Tomography as a Clinically Translatable Modality for Cancer Imaging.

William M MacCuaig, Meredith A Jones, Oshaani Abeyakoon, Lacey R McNally

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Radiology. Imaging cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  10. Evaluation of cervical lymph nodes using multispectral optoacoustic tomography: a proof-of-concept study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

William M MacCuaigStephenson Cancer Center (W.M.M., M.A.J., L.R.M.) and Department of Surgery (L.R.M.), University of Oklahoma, 755 Research Parkway, 1 Medical Center Blvd, Oklahoma City, OK 73104; Department of Biomedical Engineering, University of Oklahoma, Norman, Okla (W.M.M., M.A.J., L.R.M.); and Department of Interventional Radiology, University College Hospital London, London, England (O.A.).ORCID 0000-0002-6585-0247
Meredith A JonesStephenson Cancer Center (W.M.M., M.A.J., L.R.M.) and Department of Surgery (L.R.M.), University of Oklahoma, 755 Research Parkway, 1 Medical Center Blvd, Oklahoma City, OK 73104; Department of Biomedical Engineering, University of Oklahoma, Norman, Okla (W.M.M., M.A.J., L.R.M.); and Department of Interventional Radiology, University College Hospital London, London, England (O.A.).ORCID 0000-0001-6131-4255
Oshaani AbeyakoonStephenson Cancer Center (W.M.M., M.A.J., L.R.M.) and Department of Surgery (L.R.M.), University of Oklahoma, 755 Research Parkway, 1 Medical Center Blvd, Oklahoma City, OK 73104; Department of Biomedical Engineering, University of Oklahoma, Norman, Okla (W.M.M., M.A.J., L.R.M.); and Department of Interventional Radiology, University College Hospital London, London, England (O.A.).
Lacey R McNallyStephenson Cancer Center (W.M.M., M.A.J., L.R.M.) and Department of Surgery (L.R.M.), University of Oklahoma, 755 Research Parkway, 1 Medical Center Blvd, Oklahoma City, OK 73104; Department of Biomedical Engineering, University of Oklahoma, Norman, Okla (W.M.M., M.A.J., L.R.M.); and Department of Interventional Radiology, University College Hospital London, London, England (O.A.).ORCID 0000-0001-6756-129X
University of Oklahoma · US

Funding

Stroma Targeted Theranostic Nanoparticles for Pancreatic CancerR01CA212350 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2017 to 2021
$1.7M
Non-Invasive Detection of Tumor Extracellular pH using Multispectral Optoacoustic TomographyR01CA205941 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2016 to 2021
$1.7M
Theranostic Nanoparticles For Detection and Treatment of Pancreatic CancerR01EB020125 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2016 to 2019
$1.7M
NCI NIH HHS R01 CA205941NCI NIH HHS R01 CA212350NIBIB NIH HHS R01 EB020125
6 · The paper itself

Abstract

The use of optoacoustic imaging takes advantage of the photoacoustic effect to generate high-contrast, high-resolution medical images at penetration depths of up to 5 cm. Multispectral optoacoustic tomography (MSOT) is a type of optoacoustic imaging system that has seen promising preclinical success with a recent emergence into the clinic. Multiwavelength illumination of tissue allows for the mapping of multiple chromophores, which are generated endogenously or exogenously. However, translation of MSOT to the clinic is still in its preliminary stages. For successful translation, MSOT requires refinement of probes and data-acquisition systems to tailor to the human body, along with more intuitive, real-time visualization settings. The possibilities of optoacoustic imaging, namely MSOT, in the clinic are reviewed here. ©RSNA, 2020.

Indexed as

Photoacoustic TechniquesTomographyHumansNeoplasms

Identifiers

PMID33330850
PMCPMC7706874
OpenAlexW3107566302

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.