Evidence map›Paper›PMID 33330837›Full record

ArticleACS pharmacology & translational science2020

Prospective Evaluation of the Transparent, Elastomeric, Adaptable, Long-Lasting (TEAL) Respirator.

Adam J Wentworth, James D Byrne, Sirma Orguc, Joanna Sands, Saurav Maji, Caitlynn Tov, Sahab Babaee, Hen-Wei Huang, Hannah Boyce, Peter R Chai and 8 more

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Adam J WentworthDivision of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.
James D ByrneDivision of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.
Sirma OrgucMicrosystems Technology Laboratories, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Joanna SandsMicrosystems Technology Laboratories, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Saurav MajiMicrosystems Technology Laboratories, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Caitlynn TovDivision of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.
Sahab BabaeeDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Hen-Wei HuangDivision of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.
Hannah BoyceDivision of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.
Peter R ChaiDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, United States.
Seokkee MinDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Canchen LiDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, United States.
Jacqueline N ChuDivision of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.
Avik SomDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.
Sarah L BeckerDivision of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.
Manish GalaDivision of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.
Anantha ChandrakasanMicrosystems Technology Laboratories, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Giovanni TraversoDivision of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.

Funding

RESEARCH TRAINING IN DIGESTIVE DISEASES AND NUTRITIONT32DK007191 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1986 to 2026
$14.6M
A novel robotic wastewater analysis system to quantify opioid exposure and treatment in residential communitiesR44DA051106 · NIDA · BIOBOT ANALYTICS, INC. · PI CHAI, PETER R, MATUS GARCIA, MARIANA G · 2020 to 2022
$1.5M
Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance UsersK23DA044874 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2018 to 2022
$1.0M
NIDA NIH HHS K23 DA044874NIDA NIH HHS R44 DA051106NIDDK NIH HHS T32 DK007191
6 · The paper itself

Abstract

N95 filtering facepiece respirators (FFR) and surgical masks are essential in reducing airborne disease transmission, particularly during the COVID-19 pandemic. However, currently available FFR's and masks have major limitations, including masking facial features, waste, and integrity after decontamination. In a multi-institutional trial, we evaluated a transparent, elastomeric, adaptable, long-lasting (TEAL) respirator to evaluate success of qualitative fit test with user experience and biometric evaluation of temperature, respiratory rate, and fit of respirator using a novel sensor. There was a 100% successful fit test among participants, with feedback demonstrating excellent or good fit (90% of participants), breathability (77.5%), and filter exchange (95%). Biometric testing demonstrated significant differences between exhalation and inhalation pressures among a poorly fitting respirator, well-fitting respirator, and the occlusion of one filter of the respirator. We have designed and evaluated a transparent elastomeric respirator and a novel biometric feedback system that could be implemented in the hospital setting.

Identifiers

PMID33330837
PMCPMC7671102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.