Evidence map›Paper›PMID 33330480›Full record

ArticleFrontiers in cell and developmental biology2020

Proteasome-Mediated Regulation of Cdhr1a by Siah1 Modulates Photoreceptor Development and Survival in Zebrafish.

Warlen Pereira Piedade, Kayla Titialii-Torres, Ann C Morris, Jakub K Famulski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Warlen Pereira PiedadeDepartment of Biology, University of Kentucky, Lexington, KY, United States.
Kayla Titialii-TorresDepartment of Biology, University of Kentucky, Lexington, KY, United States.
Ann C MorrisDepartment of Biology, University of Kentucky, Lexington, KY, United States.
Jakub K FamulskiDepartment of Biology, University of Kentucky, Lexington, KY, United States.
University of Kentucky · US

Funding

Vertebrate photoreceptor development and regenerationR01EY021769 · NEI · UNIVERSITY OF KENTUCKY · PI MORRIS, ANN C · 2012 to 2022
$3.2M
Comprehensive analysis of periocular mesenchyme composition, specification and function during anterior segment formationR01EY027805 · NEI · UNIVERSITY OF KENTUCKY · PI FAMULSKI, JAKUB K · 2018 to 2022
$1.9M
NEI NIH HHS R01 EY021769NEI NIH HHS R01 EY027805
6 · The paper itself

Abstract

Congenital retinal dystrophies are a major cause of unpreventable and incurable blindness worldwide. Mutations in CDHR1, a retina specific cadherin, are associated with cone-rod dystrophy. The ubiquitin proteasome system (UPS) is responsible for mediating orderly and precise targeting of protein degradation to maintain biological homeostasis and coordinate proper development, including retinal development. Recently, our lab uncovered that the seven

Indexed as

CDHR1acell deathphotoreceptorretinaSiah E3 ubiquitin ligaseUPSzebrafish

Identifiers

PMID33330480
PMCPMC7719784
OpenAlexW3107388802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.