Evidence map›Paper›PMID 33330025›Full record

ArticleFrontiers in oncology2020

CD8+ T Cell Co-Expressed Genes Correlate With Clinical Phenotype and Microenvironments of Urothelial Cancer.

Yutao Wang, Kexin Yan, Jiaxing Lin, Yang Liu, Jianfeng Wang, Xuejie Li, Xinxin Li, Zhixiong Hua, Zhenhua Zheng, Jianxiu Shi and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yutao WangDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Kexin YanDepartment of Dermatology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Jiaxing LinDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Yang LiuDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Jianfeng WangDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Xuejie LiDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Xinxin LiDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Zhixiong HuaDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Zhenhua ZhengDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Jianxiu ShiDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Siqing SunDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
Jianbin BiDepartment of Urology, China Medical University, The First Hospital of China Medical University, Shenyang, China.
First Hospital of China Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify immune-related co-expressed genes that promote CD8

methodWe obtained bladder cancer gene matrix and clinical information data from TCGA, GSE32894 and GSE48075. The "estimate" package was used to calculate tumor purity and immune score. The CIBERSORT algorithm was used to assess CD8

resultsA CD8

conclusionThese co-expressed genes promote high levels of infiltration of CD8

Indexed as

antigen presentationbladder cancerCD8+ T cellsimmune microenvironmentweighted gene co-expression network analysis

Identifiers

PMID33330025
PMCPMC7713665
OpenAlexW3109755821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.