Evidence map›Paper›PMID 33330023›Full record

ArticleFrontiers in oncology2020

Competing Risks of Cancer and Non-Cancer Mortality When Accompanied by Lifestyle-Related Factors-A Prospective Cohort Study in Middle-Aged and Older Adults.

Pawel Macek, Malgorzata Biskup, Malgorzata Terek-Derszniak, Marta Manczuk, Halina Krol, Edyta Naszydlowska, Jolanta Smok-Kalwat, Stanislaw Gozdz, Marek Zak

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Pawel MacekInstitute of Health Sciences, Collegium Medicum, The Jan Kochanowski University, Kielce, Poland.
Malgorzata BiskupInstitute of Health Sciences, Collegium Medicum, The Jan Kochanowski University, Kielce, Poland.
Malgorzata Terek-DerszniakDepartment of Rehabilitation, Holycross Cancer Centre, Kielce, Poland.
Marta ManczukDepartment of Epidemiology and Cancer Prevention, Maria Sklodowska-Curie Institute- Oncology Center, Warsaw, Poland.
Halina KrolInstitute of Health Sciences, Collegium Medicum, The Jan Kochanowski University, Kielce, Poland.
Edyta NaszydlowskaInstitute of Health Sciences, Collegium Medicum, The Jan Kochanowski University, Kielce, Poland.
Jolanta Smok-KalwatClinical Oncology Clinic, Holycross Cancer Centre, Kielce, Poland.
Stanislaw GozdzInstitute of Health Sciences, Collegium Medicum, The Jan Kochanowski University, Kielce, Poland.
Marek ZakInstitute of Health Sciences, Collegium Medicum, The Jan Kochanowski University, Kielce, Poland.
Jan Kochanowski University · PLHoly Cross University · PLThe Maria Sklodowska-Curie National Research Institute of Oncology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe study aimed to identify the association between the lifestyle-related factors and the cancer-specific, or non-cancer-specific mortality, when accompanied by a competing risk. Two statistical methods were applied, i.e., cause-specific hazard (CSH), and sub-distribution hazard ratio (SHR). Their respective key advantages, relative to the actual study design, were addressed, as was overall application potential.

methodsSource data from 4,584 residents (34.2% men), aged 45-64 years, were processed using two different families of regression models, i.e., CSH and SHR; principal focus upon the impact of lifestyle-related factors on the competing risk of cancer and non-cancer mortality. The results were presented as hazard ratios (HR) with 95% confidence intervals (95% CI).

resultsAge, smoking status, and family history of cancer were found the leading risk factors for cancer death; the risk of non-cancer death higher in the elderly, and smoking individuals. Non-cancer mortality was strongly associated with obesity and hypertension. Moderate to vigorous physical activity decreased the risk of death caused by cancer and non-cancer causes.

conclusionsSpecific, lifestyle-related factors, instrumental in increasing overall, and cancer-specific mortality, are modifiable through health-promoting, individually pursued physical activities. Regular monitoring of such health-awareness boosting pursuits seems viable in terms of public health policy making.

Indexed as

cancercause of deathcohort studiescompeting risklifestylerisk factors

Identifiers

PMID33330023
PMCPMC7734021
OpenAlexW3109697864

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.