Evidence map›Paper›PMID 33329978›Full record

ReviewCureus2020

The Effects of Resveratrol on Telomeres and Post Myocardial Infarction Remodeling.

Sai Dheeraj Gutlapalli, Varshitha Kondapaneni, Ijeoma A Toulassi, Sujan Poudel, Mehwish Zeb, Jinal Choudhari, Ivan Cancarevic

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Aging, Cancer, and Inflammation: The Telomerase Connection.International journal of molecular sciences · 2024
    Review
  10. Review
  11. Toxicology of pharmaceutical and nutritional longevity compounds.Expert reviews in molecular medicine · 2023
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sai Dheeraj GutlapalliInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Varshitha KondapaneniInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ijeoma A ToulassiInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sujan PoudelFamily Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Mehwish ZebPediatrics, Khyber Teaching Hospital, Peshawar, PAK.
Jinal ChoudhariInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ivan CancarevicInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · USKhyber Teaching Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post myocardial infarction (MI) remodeling is the term used to define the changes in cardiac musculature after sustaining an ischemic injury. These changes decrease myocardial function and ultimately lead to heart failure. We review the contributing factors to post-MI remodeling, its association with telomere biology, as well as a myriad of other factors affecting aging and telomere length in relation to cardiovascular health. The main focus is on the effects of resveratrol in the cardiovascular system and its potential for therapeutic use in preventing long-term cardiovascular morbidity and mortality. We tried to answer important questions regarding the potential for resveratrol as a therapeutic drug to prevent adverse post-MI remodeling. In our search, we gathered 62 studies and narrowed our data down to 44 studies. The database used was PubMed, and the keywords used are "Resveratrol", "Telomere", "Post Myocardial Infarction". All the studies were carefully screened for relevant articles regarding our topic manually, Articles related to a positive association between resveratrol and its anti-aging, cardioprotective effects have been included in our study, as we could not find any articles in our search which showed a negative correlation. Our review concluded that resveratrol had pro-telomerase effects which could counter the development of adverse post-MI remodeling. Therefore resveratrol could be a useful therapeutic add-on drug to prevent cardiovascular disease. It is essential that further research including observational and large-scale clinical trials should be conducted to increase our understanding of the efficacy and viability of these novel therapeutic interventions.

Indexed as

post-myocardial infarctionresveratroltelomeres

Identifiers

PMID33329978
PMCPMC7735524
OpenAlexW3103397426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.