Evidence map›Paper›PMID 33329773›Full record

ArticleAnesthesia and pain medicine2019

The relaxant effect of nicardipine on the isolated uterine smooth muscle of the pregnant rat.

Dong Joon Kim, Mi Ha Hwang, Tae Hun An, Ki Tae Jung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anesthesia and pain medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dong Joon KimDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Korea.ORCID 0000-0002-3072-4734
Mi Ha HwangDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Korea.ORCID 0000-0002-7881-3015
Tae Hun AnDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Korea.ORCID 0000-0002-7405-0073
Ki Tae JungDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Korea.ORCID 0000-0002-2486-9961
Chosun University · KRChosun University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNicardipine, a calcium channel blocker, is used to treat hypertension in pregnancy or preterm labor. The current study was conducted to investigate the relaxant effects of nicardipine on the isolated uterine smooth muscle of the pregnant rat.

methodsWe obtained uterine smooth muscle strips from pregnant female SD rats. After uterine contraction with oxytocin 10 mU/ml, we added nicardipine (10

resultsNicardipine (10

conclusionsNicardipine relaxed and decreased the frequency of contraction of the uterine smooth muscle in a concentration-dependent pattern. It might be possible to adjust the clinical dosage of nicardipine in the obstetric field based on our results, but further clinical studies are needed to confirm them.

Indexed as

NicardipineRatRelaxationSmooth muscleUterine contractionUterus

Identifiers

PMID33329773
PMCPMC7713808
OpenAlexW2985140641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.