Evidence map›Paper›PMID 33329763›Full record

ArticleACS medicinal chemistry letters2020

Semisynthetic Analogs of the Antibiotic Fidaxomicin-Design, Synthesis, and Biological Evaluation.

Andrea Dorst, Regina Berg, Christoph G W Gertzen, Daniel Schäfle, Katja Zerbe, Myriam Gwerder, Simon D Schnell, Peter Sander, Holger Gohlke, Karl Gademann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Switching Residues: A Platform for the Synthesis of Fidaxomicin Antibiotics.Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Life (Basel, Switzerland) · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Antibiotics (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea DorstDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Regina BergDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Christoph G W GertzenInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf and John von Neumann Institute for Computing (NIC), Institute of Biological Information Processing (IBI-7: Structural Biochemistry) & Jülich Supercomputing Centre (JSC), Forschungszentrum Jülich, 40225 Düsseldorf, Germany.
Daniel SchäfleInstitute of Medical Microbiology, University of Zurich, Gloriastrasse 28/30, 8006 Zurich, Switzerland.
Katja ZerbeDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Myriam GwerderDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Simon D SchnellDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Peter SanderInstitute of Medical Microbiology, University of Zurich, Gloriastrasse 28/30, 8006 Zurich, Switzerland.
Holger GohlkeInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf and John von Neumann Institute for Computing (NIC), Institute of Biological Information Processing (IBI-7: Structural Biochemistry) & Jülich Supercomputing Centre (JSC), Forschungszentrum Jülich, 40225 Düsseldorf, Germany.
Karl GademannDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The glycoslated macrocyclic antibiotic fidaxomicin (

Identifiers

PMID33329763
PMCPMC7734799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.