ArticleFrontiers in endocrinology2020
C-Peptide: A Mediator of the Association Between Serum Uric Acid to Creatinine Ratio and Non-Alcoholic Fatty Liver Disease in a Chinese Population With Normal Serum Uric Acid Levels.
Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Global epidemiology of type 2 diabetes in patients with NAFLD or MAFLD: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- Metabolomic Pathways Distinguishing Metabolically Healthy and Unhealthy Obesity from Normal-Weight: A Cross-Sectional Study.International journal of molecular sciences · 2026Article
- Correlation Analysis of Serum Uric Acid and Uric Acid Creatinine Ratio With Sarcopenia in the Elderly.Aging medicine (Milton (N.S.W)) · 2025Article
- The association of serum uric acid level and the uric acid to creatinine ratio with non alcoholic fatty liver disease in children with obesity.Scientific reports · 2025Article
- Increased serum uric acid to creatinine ratio is associated with metabolic dysfunction associated steatotic liver disease.Scientific reports · 2025Article
- Associations between serum uric acid related ratios and the onset of metabolic dysfunction associated steatotic liver disease.Scientific reports · 2025Article
- Serum uric acid/creatinine ratio and 1-year stroke recurrence in patient with acute ischemic stroke and abnormal renal function: results from the Xi'an stroke registry study of China.Frontiers in neurology · 2025Article
- Association of serum uric acid to serum creatinine ratio with 1-year stroke outcomes in patients with acute ischemic stroke: A multicenter observational cohort study.European journal of neurology · 2024Observational
- TG: A Mediator of the Relationship of Serum Uric Acid to Creatinine Ratio and Nonalcoholic Fatty Liver Disease in Non-Obese Patients with Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- The Association of Serum Uric Acid Levels and Various Uric Acid-Related Ratios with Insulin Resistance and Obesity: A Preliminary Study in Adolescents.Children (Basel, Switzerland) · 2023Article
- Association Between Different Metabolic Markers and Metabolic Syndrome in an Outpatient Hyperuricemia Population: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Correlation between the Severity of Metabolic Dysfunction-Associated Fatty Liver Disease and Serum Uric Acid to Serum Creatinine Ratio.International journal of endocrinology · 2023Article
- Article
- Serum uric acid to creatinine ratio as a risk factor for mortality among patients on continuous ambulatory peritoneal dialysis: a multi-center retrospective study.Renal failure · 2023Article
- Serum uric acid/creatinine ratio and free androgen index are synergistically associated with increased risk of polycystic ovary syndrome in obese women.BMC endocrine disorders · 2022Article
- Association between serum uric acid-to-creatinine ratio and non-alcoholic fatty liver disease: a cross-sectional study in Chinese non-obese people with a normal range of low-density lipoprotein cholesterol.BMC gastroenterology · 2022Article
- Serum uric acid to creatinine ratio is associated with higher prevalence of NAFLD detected by FibroScan in the United States.Journal of clinical laboratory analysis · 2022Article
- The association between the serum uric acid to creatinine ratio and all-cause mortality in elderly hemodialysis patients.BMC nephrology · 2022Article
- Association of the serum uric acid to creatinine ratio with metabolic syndrome in the middle age and older population in China.Frontiers in endocrinology · 2022Article
- Relationship between Insulin Secretion and Arterial Stiffness in Essential Hypertension.International journal of hypertension · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The data on the relationship between normal-ranged serum uric acid (SUA), β-cell function, and non-alcoholic fatty liver disease (NAFLD) are complicated and insufficient. Moreover, uric acid is excreted by kidney, and SUA levels may be affected by renal function. Thus, we introduced a renal function-normalized index [serum uric acid to creatinine ratio (SUA/Cr)] into the study and explored the association between SUA/Cr, C-peptide and NAFLD in a Chinese population with normal SUA levels by a cross-sectional analysis. Materials and Methods: A total of 282 individuals with normal SUA levels and different glucose tolerance status from a diabetes project were included in the study (mean age = 53.7± 10.5 years; women = 64.50%). NAFLD was diagnosed by abdominal ultrasonography (NAFLD, n=86; without NAFLD, n=196). Trapezoid formula was used to calculate area under the curve of C-peptide (AUC Results: Individuals with NAFLD had significantly higher SUA/Cr and AUC Conclusions: SUA/Cr was positively associated with NAFLD incidence, and AUC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.