Evidence map›Paper›PMID 33329394›Full record

ArticleFrontiers in endocrinology2020

Aerobic Exercise Training Exerts Beneficial Effects Upon Oxidative Metabolism and Non-Enzymatic Antioxidant Defense in the Liver of Leptin Deficiency Mice.

Matheus Santos de Sousa Fernandes, Lucas de Lucena de Simões E Silva, Márcia Saldanha Kubrusly, Talitta Ricarlly Lopes de Arruda Lima, Cynthia Rodrigues Muller, Anna Laura Viacava Américo, Mariana Pinheiro Fernandes, Bruno Cogliati, José Tadeu Stefano, Claudia Jacques Lagranha and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Matheus Santos de Sousa FernandesLaboratório de Gastroenterologia Clínica e Experimental LIM-07, Division of Clinical Gastroenterology and Hepatology, Hospital das Clínicas HCFMUSP, Department of Gastroenterology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Lucas de Lucena de Simões E SilvaLaboratório de Gastroenterologia Clínica e Experimental LIM-07, Division of Clinical Gastroenterology and Hepatology, Hospital das Clínicas HCFMUSP, Department of Gastroenterology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Márcia Saldanha KubruslyLaboratório de Transplante e Cirurgia do Fígado (LIM-37), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Talitta Ricarlly Lopes de Arruda LimaFederal University of Pernambuco, Academic Center of Vitoria, Pernambuco, Brazil.
Cynthia Rodrigues MullerDepartment of Experimental Pathophysiology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Anna Laura Viacava AméricoDepartment of Experimental Pathophysiology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Mariana Pinheiro FernandesFederal University of Pernambuco, Academic Center of Vitoria, Pernambuco, Brazil.
Bruno CogliatiDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.
José Tadeu StefanoLaboratório de Gastroenterologia Clínica e Experimental LIM-07, Division of Clinical Gastroenterology and Hepatology, Hospital das Clínicas HCFMUSP, Department of Gastroenterology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Claudia Jacques LagranhaFederal University of Pernambuco, Academic Center of Vitoria, Pernambuco, Brazil.
Fabiana S EvangelistaSchool of Arts, Science and Humanities, University of São Paulo, São Paulo, Brazil.
Claudia P OliveiraLaboratório de Gastroenterologia Clínica e Experimental LIM-07, Division of Clinical Gastroenterology and Hepatology, Hospital das Clínicas HCFMUSP, Department of Gastroenterology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversidade de São Paulo · BRUniversidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of liver disease, which is associated with several etiological factors, including stress and dysfunction in oxidative metabolism. However, studies showed that aerobic exercise training (AET) can combat the oxidative stress (OS) and improves mitochondrial functionality in the NAFLD. To test the hypothesis that AET improves oxidative metabolism and antioxidant defense in the liver of

Indexed as

Oxidative StressPhysical Conditioning, AnimalAnimalsAntioxidantsLeptinLiverMaleMiceMice, Inbred C57BLMice, ObeseMuscle, SkeletalNon-alcoholic Fatty Liver DiseaseAntioxidantsLeptinantioxidant defenseleptin deficiencyliver diseaseoxidative metabolismphysical exercise

Identifiers

PMID33329394
PMCPMC7732625
OpenAlexW3107922137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.