Evidence map›Paper›PMID 33329349›Full record

ArticleFrontiers in neurology2020

Etoposide-Bound Magnetic Nanoparticles Designed for Remote Targeting of Cancer Cells Disseminated Within Cerebrospinal Fluid Pathways.

Herbert H Engelhard, Alexander J Willis, Syed I Hussain, Georgia Papavasiliou, David J Banner, Amanda Kwasnicki, Sajani S Lakka, Sangyeul Hwang, Tolou Shokuhfar, Sean C Morris and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Herbert H EngelhardDepartment of Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States.
Alexander J WillisDepartment of Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States.
Syed I HussainDepartment of Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States.
Georgia PapavasiliouDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States.
David J BannerDepartment of Bioengineering University of Illinois at Chicago, Chicago, IL, United States.
Amanda KwasnickiDepartment of Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States.
Sajani S LakkaDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Sangyeul HwangIMRA America, Inc., Ann Arbor, MI, United States.
Tolou ShokuhfarDepartment of Bioengineering University of Illinois at Chicago, Chicago, IL, United States.
Sean C MorrisPulse Therapeutics, Inc., St. Louis, MO, United States.
Bing LiuIMRA America, Inc., Ann Arbor, MI, United States.
University of Illinois Chicago · USIMRA America (United States)Illinois Institute of Technology · USPulse Biosciences (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic nanoparticles (MNPs) have potential for enhancing drug delivery in selected cancer patients, including those which have cells that have disseminated within cerebrospinal fluid (CSF) pathways. Here, we present data related to the creation and

Indexed as

cerebrospinal fluidglioblastomaleptomeningeal metastaseslung cancermagnetic drug targetingmedulloblastomananoparticles

Identifiers

PMID33329349
PMCPMC7729165
OpenAlexW3110328839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.