Evidence map›Paper›PMID 33329154›Full record

ArticleFrontiers in psychiatry2020

EEG Microstate Differences in Medicated vs. Medication-Naïve First-Episode Psychosis Patients.

Amatya J Mackintosh, Stefan Borgwardt, Erich Studerus, Anita Riecher-Rössler, Renate de Bock, Christina Andreou

Abstract read
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Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  7. Electroencephalography microstates imbalance across the spectrum of early psychosis, autism, and mood disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2023
    Article
  8. [Advances in methods and applications of electroencephalogram microstate analysis].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amatya J MackintoshDivision of Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland.
Stefan BorgwardtUniversity Psychiatric Clinics (UPK) Basel, University of Basel, Basel, Switzerland.
Erich StuderusDivision of Personality and Developmental Psychology, Department of Psychology, University of Basel, Basel, Switzerland.
Anita Riecher-RösslerFaculty of Medicine, University of Basel, Basel, Switzerland.
Renate de BockDivision of Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland.
Christina AndreouDivision of Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been considerable interest in the role of synchronous brain activity abnormalities in the pathophysiology of psychotic disorders and their relevance for treatment; one index of such activity are EEG resting-state microstates. These reflect electric field configurations of the brain that persist over 60-120 ms time periods. A set of quasi-stable microstates classes A, B, C, and D have been repeatedly identified across healthy participants. Changes in microstate parameters coverage, duration and occurrence have been found in medication-naïve as well as medicated patients with psychotic disorders compared to healthy controls. However, to date, only two studies have directly compared antipsychotic medication effects on EEG microstates either pre- vs. post-treatment or between medicated and unmedicated chronic schizophrenia patients. The aim of this study was therefore to directly compare EEG resting-state microstates between medicated and medication-naïve (untreated) first-episode (FEP) psychosis patients (mFEP vs. uFEP). We used 19-channel clinical EEG recordings to compare temporal parameters of four prototypical microstate classes (A-D) within an overall sample of 47 patients (mFEP

Indexed as

antipsychoticelectroencephalographyneurolepticpathophysiologyresting-stateschizophreniaunmedicateduntreated

Identifiers

PMID33329154
PMCPMC7732503

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.