ArticleFrontiers in human neuroscience2020
Abnormal Connectivity and Brain Structure in Patients With Visual Snow.
Article in Frontiers in human neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Visual Snow Syndrome as a Network Disorder: A Systematic Review.Frontiers in neurology · 2021Pooled it
- Unmasking the noise: aberrant cortical oscillations in visual snow syndrome.The journal of headache and pain · 2026Article
- Enhanced neural plasticity of the primary visual cortex in visual snow syndrome: evidence from magnetoencephalographic gamma oscillations.Brain communications · 2026Article
- Somatosensory perception in Visual Snow Syndrome: a comparison to age-, sex- and migraine-matched controls using Quantitative Sensory Testing - no evidence of altered somatosensory thresholds.The journal of headache and pain · 2025Article
- Assessing the impact of fetal growth restriction using high-resolution MRI: a comprehensive cortical analysis.BMC pregnancy and childbirth · 2025Article
- Visual Snow Is Susceptible to the Motion Aftereffect.Investigative ophthalmology & visual science · 2025Article
- Altered functional connectivity strength between structurally and functionally affected brain regions in visual snow syndrome.Brain communications · 2025Article
- [Characterization of a German cohort with visual snow syndrome].Der Nervenarzt · 2024Article
- Alterations of the alpha rhythm in visual snow syndrome: a case-control study.The journal of headache and pain · 2024Article
- Visual Snow: Updates and Narrative Review.Current pain and headache reports · 2024Review
- Understanding visual perception in visual snow syndrome: a battery of psychophysical tests plus the 30-day clinical diary.Brain communications · 2024Article
- Adapting to Visual Noise Alleviates Visual Snow.Investigative ophthalmology & visual science · 2023Article
- Visual snow syndrome and migraine: a review.Eye (London, England) · 2023Review
- Visual Snow: A Review on Pathophysiology and Treatment.Journal of clinical medicine · 2023Review
- Visual Disturbances Spectrum in Pediatric Migraine.Journal of clinical medicine · 2023Review
- Brain network dynamics in people with visual snow syndrome.Human brain mapping · 2023Article
- SimultaneousEJNMMI research · 2022Article
- The impact of levamisole and alcohol on white matter microstructure in adult chronic cocaine users.Addiction biology · 2022Article
- Editorial: Visual Snow: Old Problem, New Understanding.Frontiers in neurology · 2022Article
- Article
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveVisual snow (VS) is a distressing, life-impacting condition with persistent visual phenomena. VS patients show cerebral hypermetabolism within the visual cortex, resulting in altered neuronal excitability. We hypothesized to see disease-dependent alterations in functional connectivity and gray matter volume (GMV) in regions associated with visual perception.
methodsNineteen patients with VS and 16 sex- and age-matched controls were recruited. Functional magnetic resonance imaging (fMRI) was applied to examine resting-state functional connectivity (rsFC). Volume changes were assessed by means of voxel-based morphometry (VBM). Finally, we assessed associations between MRI indices and clinical parameters.
resultsPatients with VS showed hyperconnectivity between extrastriate visual and inferior temporal brain regions and also between prefrontal and parietal (angular cortex) brain regions (
conclusionThis study found VS to be associated with both functional and structural changes in the early and higher visual cortex, as well as the temporal cortex. These brain regions are involved in visual processing, memory, spatial attention, and cognitive control. We conclude that VS is not just confined to the visual system and that both functional and structural changes arise in VS patients, be it as an epiphenomenon or a direct contributor to the pathomechanism of VS. These
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.