Evidence map›Paper›PMID 33328922›Full record

ArticleFrontiers in behavioral neuroscience2020

Divergent Effects of Systemic and Intracollicular CB Receptor Activation Against Forebrain and Hindbrain-Evoked Seizures in Rats.

Victor R Santos, Robert Hammack, Evan Wicker, Prosper N'Gouemo, Patrick A Forcelli

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Victor R SantosDepartment of Pharmacology and Physiology, Georgetown University School of Medicine, Washington, DC, United States.
Robert HammackDepartment of Pharmacology and Physiology, Georgetown University School of Medicine, Washington, DC, United States.
Evan WickerDepartment of Pharmacology and Physiology, Georgetown University School of Medicine, Washington, DC, United States.
Prosper N'GouemoDepartment of Pediatrics, Georgetown University School of Medicine, Washington, DC, United States.
Patrick A ForcelliDepartment of Pharmacology and Physiology, Georgetown University School of Medicine, Washington, DC, United States.
Georgetown University · USThe University of Texas Health Science Center at San Antonio · USUniversidade Federal de Minas Gerais · BR

Funding

Optogenetic control of seizures via the basal gangliaR01NS097762 · NINDS · GEORGETOWN UNIVERSITY · PI Patrick Alexander Forcelli · 2016 to 2026
$4.1M
NINDS NIH HHS R01 NS097762
6 · The paper itself

Abstract

Cannabinoid (CB) receptor agonists are of growing interest as targets for anti-seizure therapies. Here we examined the effect of systemic administration of the CB receptor agonist WIN 55,212-2 (WIN) against audiogenic seizures (AGSs) in the Genetically Epilepsy Prone Rat (GEPR)-3 strain, and against seizures evoked focally from the

Indexed as

area tempestascannabinoidgenetically epilepsy prone rat (GEPR)piriform cortexsuperior colliculus (SC)

Identifiers

PMID33328922
PMCPMC7718031
OpenAlexW3098454366

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.