Evidence map›Paper›PMID 33328903›Full record

ArticleFrontiers in neuroanatomy2020

HPG-Dependent Peri-Pubertal Regulation of Adult Neurogenesis in Mice.

Sara Trova, Serena Bovetti, Giuliana Pellegrino, Sara Bonzano, Paolo Giacobini, Paolo Peretto

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sara TrovaDepartment of Life Sciences and Systems Biology, Neuroscience Institute Cavalieri Ottolenghi, University of Torino, Orbassano, Italy.
Serena BovettiDepartment of Life Sciences and Systems Biology, Neuroscience Institute Cavalieri Ottolenghi, University of Torino, Orbassano, Italy.
Giuliana PellegrinoUniv.Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience and Cognition, Laboratory of the Development and Plasticity of Neuroendocrine Brain, Lille, France.
Sara BonzanoDepartment of Life Sciences and Systems Biology, Neuroscience Institute Cavalieri Ottolenghi, University of Torino, Orbassano, Italy.
Paolo GiacobiniUniv.Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience and Cognition, Laboratory of the Development and Plasticity of Neuroendocrine Brain, Lille, France.
Paolo PerettoDepartment of Life Sciences and Systems Biology, Neuroscience Institute Cavalieri Ottolenghi, University of Torino, Orbassano, Italy.
Neuroscience Institute · ITCentre Hospitalier Universitaire de Lille · FRLille Neurosciences & Cognition

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult neurogenesis, a striking form of neural plasticity, is involved in the modulation of social stimuli driving reproduction. Previous studies on adult neurogenesis have shown that this process is significantly modulated around puberty in female mice. Puberty is a critical developmental period triggered by increased secretion of the gonadotropin releasing hormone (GnRH), which controls the activity of the hypothalamic-pituitary-gonadal axis (HPG). Secretion of HPG-axis factors at puberty participates to the refinement of neural circuits that govern reproduction. Here, by exploiting a transgenic GnRH deficient mouse model, that progressively loses GnRH expression during postnatal development (

Indexed as

accessory olfactory bulbadult neurogenesisdentate gyrusGnRHhypothalamus-pituitary-gonadal axismain olfactory bulbpubertysubventricular zone

Identifiers

PMID33328903
PMCPMC7732626
OpenAlexW3110582717

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.