Evidence map›Paper›PMID 33328791›Full record

ArticleActa ortopedica brasileira

EFFECT OF PKP ON SERUM SOST IN PATIENTS WITH VERTEaBRAL COMPRESSION FRACTURES.

Enzhi Wang, Jianjun Lin, Guangwei Xu, Xinhua Wang, Mifang Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta ortopedica brasileira. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 14 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Enzhi WangTaizhou Integrated Chinese and Western Medicine Hospital, Department of Clinical Laboratory, Taizhou, Zhejiang, China.ORCID 0000-0003-0309-0251
Jianjun LinNingbo Fourth Hospital, Department of Clinical Laboratory, Ningbo, Zhejiang, China.ORCID 0000-0002-3727-0632
Guangwei XuNingbo Women and Children's Hospital, Department of Orthopedics, Ningbo, Zhejiang, China.ORCID 0000-0003-2983-305X
Xinhua WangTaizhou Integrated Chinese and Western Medicine Hospital, Department of Clinical Laboratory, Taizhou, Zhejiang, China.ORCID 0000-0002-8620-1596
Mifang ChenNingbo Women and Children's Hospital, Department of Clinical Laboratory, Ningbo, Zhejiang, China.ORCID 0000-0001-7443-0693
Ningbo No. 2 Hospital · CNWenzhou Medical University · CNNingbo No.6 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study sought to determine serum sclerostin (SOST) expression in patients with osteoporotic thoracolumbar vertebral compression fractures before and after percutaneous kyphoplasty (PKP).

methodsSerum SOST levels were quantified with a sandwich enzyme-linked immunosorbent assay (ELISA) preoperatively and six months postoperatively. Anterior vertebral height, kyphotic angles, and Visual Analogue Scale (VAS) scores were also recorded.

resultsSerum SOST was highly expressed in patients and remained negatively correlated with bone mineral density (BMD). Vertebral heights, local kyphotic angles, and VAS scores were all significantly improved after PKP. However, serum SOST was positively correlated with BMD six months after surgery.

conclusionPKP was an effective treatment strategy for osteoporotic thoracolumbar vertebral compression fractures, improving BMD and decreasing serum SOST levels.

Indexed as

Bone DensityKyphoplastyOsteoporosis

Identifiers

PMID33328791
PMCPMC7723380
OpenAlexW3111934624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.