ArticleNature2021
Measuring DNA mechanics on the genome scale.
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Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.
0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
87 citing papers in PubMed, 157 citations in OpenAlex.
- Single-molecule imaging reveals DNA shape read-out by the INO80 chromatin remodeler.Nature communications · 2026Article
- Visualizing poloidal orientation in DNA minicircles.Biophysical journal · 2026Article
- Positional interpretation of cis-regulatory code and nucleosome organization with deep learning models.Nature communications · 2026Article
- Searching for sequence features that control DNA cyclizability.PNAS nexus · 2026Article
- Physics-based nucleosome-resolution modeling of epigenetic-driven chromatin domain dynamics.Nucleic acids research · 2026Article
- DNA Mechanical Strain Steers Transcription Factor Recognition.Research square · 2026Article
- cgNA+min: computation of sequence-dependent dsDNA energy-minimizing minicircles.Nucleic acids research · 2026Article
- Differential nucleosome organization in human interphase and metaphase chromosomes.Molecular systems biology · 2026Article
- Multi-scale dissection, compaction and derivatization of mammalian developmental enhancers.bioRxiv : the preprint server for biology · 2026Article
- The Fluid Mosaic Model of chromatin organization: integrating dynamics, conformational heterogeneity and multiscale organization.Communications biology · 2026Review
- Genome-wide DNA supercoiling arises from transcription and SMC activity and mediates transcriptional negative feedback.bioRxiv : the preprint server for biology · 2026Article
- Multiplexed single-molecule characterization at the library scale.Nature protocols · 2026Review
- Mlh1-Pms1 couples ATP-driven DNA compaction with nick-dependent endonuclease activation.Nucleic acids research · 2025Article
- Chromatin unfolding via loops can drive clustered transposon insertion.Biophysical journal · 2025Article
- Differential nucleosome organization in human interphase and metaphase chromosomes.bioRxiv : the preprint server for biology · 2025Article
- The INO80 chromatin remodeller facilitates DNA damage bypass via postreplicative gap repair.The EMBO journal · 2025Article
- DNA bendability regulates transcription factor binding to nucleosomes.Nature structural & molecular biology · 2025Article
- Coarse-grained mathematical models for studying mechanical properties of the DNA.Biophysical reviews · 2025Review
- Sequence-Dependent Shape and Stiffness of DNA and RNA Double Helices: Hexanucleotide Scale and Beyond.Journal of chemical information and modeling · 2025Article
- Article
27 more citing papers are in PubMed but not listed here.
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Authors and funding
15 authors at 4 institutions in 2 countries.
Aakash BasuDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-2446-4937
Dmitriy G BobrovnikovDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-0696-6829
Zan QureshiDepartment of Biophysics, Johns Hopkins University, Baltimore, MD, USA.
Tunc KayikciogluDepartment of Physics, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Thuy T M NgoDepartment of Physics, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID http://orcid.org/0000-0002-0751-8983
Anand RanjanDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Sebastian EustermannDepartment of Biochemistry, Ludwig-Maximilians-Universität, Munich, Germany.
Basilio CiezaDepartment of Biophysics, Johns Hopkins University, Baltimore, MD, USA.
Michael T MorganDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Miroslav HejnaDepartment of Physics, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID http://orcid.org/0000-0002-3613-1796
H Tomas RubeDepartment of Physics, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Karl-Peter HopfnerDepartment of Biochemistry, Ludwig-Maximilians-Universität, Munich, Germany.ORCID http://orcid.org/0000-0002-4528-8357
Cynthia WolbergerDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-8578-2969
Jun S SongDepartment of Physics, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Taekjip HaDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tjha@jhu.edu.ORCID http://orcid.org/0000-0003-2195-6258
Johns Hopkins University · USUniversity of Illinois Urbana-Champaign · USLudwig-Maximilians-Universität München · DEHoward Hughes Medical Institute · US
Funding
Mechanistic studies of chromatin modification in transcription regulationR35GM130393 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Cynthia Wolberger · 2019 to 2026
$7.3MPredicting Transcriptional and Epigenetic Networks in Cancer from Sequencing DataR01CA163336 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Jun S Song · 2012 to 2026
$4.4MSingle Molecule Studies of Nucleic Acids RemodelingR35GM122569 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Taekjip Ha · 2017 to 2026
$3.5MEuropean Research Council 833613Howard Hughes Medical InstituteNCI NIH HHS R01 CA163336NIGMS NIH HHS R35 GM122569NIGMS NIH HHS R35 GM130393NIH HHS GM122569
Abstract
Mechanical deformations of DNA such as bending are ubiquitous and have been implicated in diverse cellular functions
Indexed as
Biomechanical PhenomenaGenome, FungalChromatin Assembly and DisassemblyCodonDNA, FungalNucleosomesPliabilitySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription Initiation SiteCodonDNA, FungalINO80 complex, S cerevisiaeNucleosomesSaccharomyces cerevisiae Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.