Trial reportScientific reports2020
Effects of different irrigation protocols on dentin surfaces as revealed through quantitative 3D surface texture analysis.
Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of Endodontic Irrigation on Mineral Content of Root Canal Dentine: A Systematic Review and Meta-Analysis.European endodontic journal · 2023Pooled it
- Comparison of sealer penetration of sonic activation versus conventional needle irrigation: a systematic review and meta-analysis of randomized controlled trials.BMC oral health · 2022Pooled it
- Effects of Continuous Chelation with Etidronate on Mechanical Properties of the Root Canal Dentin: A Systematic Review with Meta-Analysis.Dentistry journal · 2026Review
- Assessment of sealing ability, antibacterial effect and marginal adaptation of bioactive materials in pulpotomized primary molars: an in-vitro study.BMC oral health · 2026Article
- Influence of endodontic irrigants on hydraulic cements: solubility, color alteration and surface changes.European oral research · 2026Article
- Evaluating the penetration, interfacial adaptation, and push-out bond strength of four bioceramic-based root canal sealers.BMC oral health · 2025Article
- Nanotechnology and Its Application in Dentistry: A Systematic Review of Recent Advances and Innovations.Journal of clinical medicine · 2024Review
- Effect of herbal irrigants on surface roughness of intraradicular dentin using quantitative method of 3D surface texture analysis.Scientific reports · 2024Article
- Mechanical properties of simulated dentin caries treated with metal cations and L-ascorbic acid 2-phosphate.Odontology · 2024Article
- A Novel pH-Responsive Nano-Sized Lanthanum-Doped Polyvinyl Alcohol-Carbon Quantum Dot Composite for Root Canal Irrigation.International journal of nanomedicine · 2024Article
- 2D and 3D Erosion Landscape Analysis of Endodontic-Treated Teeth Using EDTA and HEDP as Chelating Agents: A High-Resolution Micro-Computed Tomographic Study.Dentistry journal · 2023Article
- Antibacterial and smear layer removal efficacy of moringa (Journal of Taibah University Medical Sciences · 2023Article
- Minimally invasive management of vital teeth requiring root canal therapy.Scientific reports · 2023Article
- Efficacy of Different Root Canal Irrigating Solutions in Removing Smear Layer: A Scanning Electron Microscopic Study.Cureus · 2023Article
- Reparative dentin formation as a possible factor influencing the penetrability of dentin in human teeth with apical periodontitis: an ex vivo study.BMC oral health · 2023Article
- Bacterial Colonization and Proliferation in Primary Molars following the Use of the Hall Technique: A Confocal Laser Scanning Microscopy Study.Children (Basel, Switzerland) · 2023Article
- Three-Dimensional Surface Texture Analysis of Fluoride's Effect on Enamel Erosion.Journal of clinical medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The combination of ethylenediaminetetraacetic acid (EDTA) and sodium hypochlorite (NaOCl) has been advocated as an effective irrigation methodology to remove organic and inorganic matter in root canal therapy. Yet, it was suggested that both solutions might lead to structural changes of the dentinal wall surface, depending on the order of application which might affect sealer mechanical retention. This study aims to evaluate the effect of different irrigating protocols on dentin surface roughness using quantitative 3D surface texture analysis. Data stems from 150 human root dentin sections, divided into five groups, each prepared according to one of the following protocols: Negative control; 17% EDTA; 17% EDTA followed by 5.25% NaOCl; 5.25% NaOCl; and 5.25% NaOCl followed by 17% EDTA. Each dentin sample was examined for its three-dimensional surface texture using a high-resolution confocal disc-scanning measuring system. EDTA 17% and the combined EDTA 17% with NaOCl 5.25% showed considerably higher roughness properties compared to the control and to NaOCl 5.25% alone. However, the irrigation sequence did not affect the dentin roughness properties. Therefore, mechanical retention is probably not dependent upon the selection of irrigation protocol sequence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.