Evidence map›Paper›PMID 33328493›Full record

ArticleScientific reports2020

Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor.

Thomas Imhof, Katharina Rosenblatt, Galyna Pryymachuk, Daniela Weiland, Nicolas Noetzel, James Deschner, Olivier R Baris, Sammy Kimoloi, Manuel Koch, Rudolf J Wiesner and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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  7. Mitochondria modulate ameloblast CaFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Thomas ImhofInstitute for Experimental Dental Research and Oral Musculoskeletal Biology, Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.
Katharina RosenblattCenter for Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty, University of Cologne, Robert-Koch-Strasse 39, 50931, Cologne, Germany.
Galyna PryymachukDepartment of Anatomy, University of Cologne, Cologne, Germany.
Daniela WeilandCenter for Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty, University of Cologne, Robert-Koch-Strasse 39, 50931, Cologne, Germany.
Nicolas NoetzelCenter for Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty, University of Cologne, Robert-Koch-Strasse 39, 50931, Cologne, Germany.
James DeschnerDepartment of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, Augustusplatz 2, 55131, Mainz, Germany.
Olivier R BarisEquipe MitoLab, UMR CNRS 6015, INSERM U1083, Institut MitoVasc, Université d'Angers, Angers, France.
Sammy KimoloiCenter for Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty, University of Cologne, Robert-Koch-Strasse 39, 50931, Cologne, Germany.
Manuel KochInstitute for Experimental Dental Research and Oral Musculoskeletal Biology, Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.
Rudolf J WiesnerCenter for Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty, University of Cologne, Robert-Koch-Strasse 39, 50931, Cologne, Germany. rudolf.wiesner@uni-koeln.de.
Yüksel KorkmazDepartment of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, Augustusplatz 2, 55131, Mainz, Germany. yueksel.korkmaz@unimedizin-mainz.de.
University of Cologne · DEJohannes Gutenberg University Mainz · DECentre National de la Recherche Scientifique · FRUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The formation of dentin and enamel matrix depends on reciprocal interactions between epithelial-mesenchymal cells. To assess the role of mitochondrial function in amelogenesis and dentinogenesis, we studied postnatal incisor development in K320E-Twinkle

Indexed as

Oxidative PhosphorylationAmelogeninAnimalsAnimals, NewbornDental EnamelDentinElectron Transport Complex IVEpithelial CellsIncisorMice, TransgenicMitochondriaMutationSuccinate DehydrogenaseAmelogeninElectron Transport Complex IVSuccinate Dehydrogenase

Identifiers

PMID33328493
PMCPMC7744519
OpenAlexW3110676722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.