ArticleHorticulture research2020
WUSCHEL-related homeobox1 (WOX1) regulates vein patterning and leaf size in Cucumis sativus.
Article in Horticulture research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- Newly found functions and regulatory networks of WOX family: what else does the WOX say?Planta · 2026Review
- Engineering TadA8e-based base editors for GhWOX1 editing to create cotton with diverse leaf shapes.Science China. Life sciences · 2026Article
- Transcriptomic and metabolomic changes associated with the induction and initiation of juice sacs in citrus fruit.Planta · 2026Article
- Overexpression of PeonyPlants (Basel, Switzerland) · 2025Article
- Comprehensive analysis and identification of the WOX gene family in Schima superba and the key gene SsuWOX1 for enhancing callus regeneration capacity.BMC plant biology · 2025Article
- WOX1 controls leaf serration development via temporally restricting BRASSINAZOLE RESISTANT 1 and CUP SHAPED COTYLEDON 3 expression in Arabidopsis.Journal of experimental botany · 2025Article
- Functional Analysis ofInternational journal of molecular sciences · 2024Article
- Plant Growth Regulators: An Overview of WOX Gene Family.Plants (Basel, Switzerland) · 2024Review
- CsHLS1-CsSCL28 module regulates compact plant architecture in cucumber.Plant biotechnology journal · 2024Article
- NnWOX1-1, NnWOX4-3, and NnWOX5-1 of lotus (Nelumbo nucifera Gaertn)promote root formation and enhance stress tolerance in transgenic Arabidopsis thaliana.BMC genomics · 2023Article
- Integrating genome-wide association and transcriptome analysis to provide molecular insights into heterophylly and eco-adaptability in woody plants.Horticulture research · 2023Article
- Genome-Wide Identification and Characterization Analysis of WUSCHEL-Related Homeobox Family in Melon (International journal of molecular sciences · 2023Article
- ZmHOX32 is related to photosynthesis and likely functions in plant architecture of maize.Frontiers in plant science · 2023Article
- Research Progress on the Leaf Morphology, Fruit Development and Plant Architecture of the Cucumber.Plants (Basel, Switzerland) · 2022Review
- Morphological Characterization and Integrated Transcriptome and Proteome Analysis ofInternational journal of molecular sciences · 2022Article
- Genome-Wide Identification and Comparative Analysis ofFrontiers in genetics · 2022Article
- Overexpression of PvWOX3a in switchgrass promotes stem development and increases plant height.Horticulture research · 2021Article
- Leaf Size Development Differences and Comparative Trancriptome Analyses of Two Poplar Genotypes.Genes · 2021Article
- Characterization of phytohormone and transcriptome profiles during protocorm-like bodies development of Paphiopedilum.BMC genomics · 2021Article
- Genetic regulation of shoot architecture in cucumber.Horticulture research · 2021Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, WUSCHEL-related homeobox1 (WOX1) homologs promote lamina mediolateral outgrowth. However, the downstream components linking WOX1 and lamina development remain unclear. In this study, we revealed the roles of WOX1 in palmate leaf expansion in cucumber (Cucumis sativus). A cucumber mango fruit (mf) mutant, resulting from truncation of a WOX1-type protein (CsWOX1), displayed abnormal lamina growth and defects in the development of secondary and smaller veins. CsWOX1 was expressed in the middle mesophyll and leaf margins and rescued defects of the Arabidopsis wox1 prs double mutant. Transcriptomic analysis revealed that genes involved in auxin polar transport and auxin response were highly associated with leaf development. Analysis of the cucumber mf rl (round leaf) double mutant revealed that CsWOX1 functioned in vein development via PINOID (CsPID1)-controlled auxin transport. Overexpression of CsWOX1 in cucumber (CsWOX1-OE) affected vein patterning and produced 'butterfly-shaped' leaves. CsWOX1 physically interacted with CsTCP4a, which may account for the abnormal lamina development in the mf mutant line and the smaller leaves in the CsWOX1-OE plants. Our findings demonstrated that CsWOX1 regulates cucumber leaf vein development by modulating auxin polar transport; moreover, CsWOX1 regulates leaf size by controlling CIN-TCP genes.
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