Evidence map›Paper›PMID 33328413›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Chronic Enteropathy Associated with SLCO2A1 with Pachydermoperiostosis.

Yoshikazu Tsuzuki, Ryutaro Aoyagi, Kazuya Miyaguchi, Keigo Ashitani, Hideki Ohgo, Minoru Yamaoka, Keisuke Ishizawa, Hidekazu Kayano, Tadakazu Hisamatsu, Junji Umeno and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Yoshikazu TsuzukiDepartment of General Internal Medicine, Saitama Medical University, Japan.
Ryutaro AoyagiDepartment of General Internal Medicine, Saitama Medical University, Japan.
Kazuya MiyaguchiDepartment of General Internal Medicine, Saitama Medical University, Japan.
Keigo AshitaniDepartment of General Internal Medicine, Saitama Medical University, Japan.
Hideki OhgoDepartment of General Internal Medicine, Saitama Medical University, Japan.
Minoru YamaokaDepartment of General Internal Medicine, Saitama Medical University, Japan.
Keisuke IshizawaDepartment of Pathology, Saitama Medical University, Japan.
Hidekazu KayanoDepartment of Pathology, Saitama Medical University, Japan.
Tadakazu HisamatsuThe Third Department of Internal Medicine, Kyorin University School of Medicine, Japan.
Junji UmenoDepartment of Medicine and Clinical Science, Graduate School of Medical Science, Kyushu University, Japan.
Naoki HosoeCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Japan.
Takayuki MatsumotoDivision of Gastroenterology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Japan.
Hidetomo NakamotoDepartment of General Internal Medicine, Saitama Medical University, Japan.
Hiroyuki ImaedaDepartment of General Internal Medicine, Saitama Medical University, Japan.
Saitama Medical University · JPIwate Medical University · JPKeio University · JPKyorin University · JPKyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 49-year-old man complained of chronic palpitation and shortness of breath, which had recently become exacerbated. A blood examination indicated severe refractory anemia and hypoproteinemia. Physical examinations revealed anemia, a systolic murmur, and spoon nails. Multiple nonspecific ileal ulcers were observed. A pathological examination indicated a small granuloma with CD68-positive histiocytes. He had a deeply wrinkled forehead, chiseled face, and clubbed fingers. Radiography revealed periostosis of the fingers and long bones in the limb. He was diagnosed with pachydermoperiostosis. SLCO2A1 demonstrated a c.1807C>T homo-mutation. He was also diagnosed with SLCO2A1-associated chronic enteropathy and thus was treated with 5-aminosalicylic acid, which temporarily improved the ileal ulcers, anemia, and hypoalbuminemia.

Indexed as

Inflammatory Bowel DiseasesOrganic Anion TransportersOsteoarthropathy, Primary HypertrophicHumansMaleMiddle AgedMutationUlcerOrganic Anion TransportersSLCO2A1 protein, humanCEASpachydermoperiostosisSLCO2A1

Identifiers

PMID33328413
PMCPMC7807103
OpenAlexW3111022321

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.