ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
An Angiotensin-Responsive Connection from the Lamina Terminalis to the Paraventricular Nucleus of the Hypothalamus Evokes Vasopressin Secretion to Increase Blood Pressure in Mice.
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Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21citing papers in PubMed
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Who cites it
21 citing papers in PubMed, 30 citations in OpenAlex.
- Oxytocin and Vasopressin Cross Talk Within the Brain Increases Blood Pressure.Circulation research · 2026Article
- Central Osmolality Sensing for Arginine Vasopressin Release Is Mediated by WNK1-OSR1/SPAK-Kv3.1 Cascade.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- A novel approach to the prevention and management of cardiovascular diseases: targeting brain-heart axis.European journal of medical research · 2025Review
- Distinct neural representations of hunger and thirst in neonatal mice before the emergence of food- and water-seeking behaviors.Current biology : CB · 2025Article
- Neurons of the Central Nucleus of the Amygdala That Express Angiotensin Type 2 Receptors Couple Lowered Blood Pressure with Anxiolysis in Male Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- [Mechanisms by Which Paraventricular Hypothalamic Nucleus Participates in the Acupuncture Treatment of Diseases].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Review
- A neural perspective on the treatment of hypertension: the neurological network excitation and inhibition (E/I) imbalance in hypertension.Frontiers in cardiovascular medicine · 2024Review
- Role of Inflammatory Processes in the Brain-Body Relationship Underlying Hypertension.Current hypertension reports · 2023Review
- Uncovering the brain-wide pattern of synaptic input to vasopressin-expressing neurons in the paraventricular nucleus of the hypothalamus.The Journal of comparative neurology · 2023Article
- WNK1 promotes water homeostasis by acting as a central osmolality sensor for arginine vasopressin release.The Journal of clinical investigation · 2023Article
- Sodium Intake and Disease: Another Relationship to Consider.Nutrients · 2023Review
- Transcranial Direct Current Stimulation in the Management of Hypertension: A Plausible Hypothesis?Arquivos brasileiros de cardiologia · 2023Article
- The organum vasculosum of the lamina terminalis and subfornical organ: regulation of thirst.Frontiers in neuroscience · 2023Review
- Renin-a in the Subfornical Organ Plays a Critical Role in the Maintenance of Salt-Sensitive Hypertension.Biomolecules · 2022Article
- Neuroimmune axis of cardiovascular control: mechanisms and therapeutic implications.Nature reviews. Cardiology · 2022Review
- A Novel Organ-Specific Approach to Selectively Target Sensory Afferents Innervating the Aortic Arch.Frontiers in physiology · 2022Article
- Activation of the Organum Vasculosum of the Lamina Terminalis Produces a Sympathetically Mediated Hypertension.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Cardiovascular Neuroendocrinology: Emerging Role for Neurohypophyseal Hormones in Pathophysiology.Endocrinology · 2021Review
- Preoptic BRS3 neurons increase body temperature and heart rate via multiple pathways.Cell metabolism · 2021Article
- Identification of Novel Cross-Talk between the Neuroendocrine and Autonomic Stress Axes Controlling Blood Pressure.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Charles J FrazierDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Scott W HardenDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Amy R AlleyneDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Mazher MohammedDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Wanhui ShengDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Justin A SmithDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Khalid ElsaafienDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Eliot A SpectorDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Dominique N JohnsonDepartment of Physiology and Functional Genomics, College of Medicine, University of Florida, Gainesville, Florida 32611.
Karen A ScottDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Eric G KrauseDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32611.
Annette D de KloetCenter for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, Florida 32611 adekloet@ufl.edu.
University of Florida · US
Funding
Interrogating stress-relieving neural circuits to alleviate cardiovascular diseaseR35HL150750 · NHLBI · UNIVERSITY OF FLORIDA · PI Eric Gerald Krause · 2020 to 2026
$5.9MNeurons expressing angiotensin type 2 receptors in the NTS as an access point for cardiovascular control.R01HL136595 · NHLBI · UNIVERSITY OF FLORIDA · PI COLIN SUMNERS, Annette Diane de Kloet · 2018 to 2026
$4.8MInterrogating distinct angiotensin type-1 and type-2 receptor containing brain circuits to understand and alleviate hypertensionR01HL145028 · NHLBI · UNIVERSITY OF FLORIDA · PI DE KLOET, ANNETTE DIANE · 2019 to 2023
$1.9MCentral Mechanisms Underlying the Stress Dampening Effects of Acute HypernatremiaR01HL122494 · NHLBI · UNIVERSITY OF FLORIDA · PI KRAUSE, ERIC GERALD · 2015 to 2019
$1.9MNovel role of central AT2R in blood pressure regulationR00HL125805 · NHLBI · UNIVERSITY OF FLORIDA · PI DE KLOET, ANNETTE DIANE · 2016 to 2018
$746kCentral Angiotensin receptors and teh neural control of homeostasisR00HL096830 · NHLBI · UNIVERSITY OF FLORIDA · PI KRAUSE, ERIC GERALD · 2011 to 2013
$727kCentral AT1 receptors and the integrated stress response.K99HL096830 · NHLBI · UNIVERSITY OF CINCINNATI · PI KRAUSE, ERIC GERALD · 2009 to 2010
$248kNovel role of central AT2R in blood pressure regulationK99HL125805 · NHLBI · UNIVERSITY OF FLORIDA · PI DE KLOET, ANNETTE DIANE · 2015 to 2016
$225kNHLBI NIH HHS K99 HL096830NHLBI NIH HHS K99 HL125805NHLBI NIH HHS R00 HL096830NHLBI NIH HHS R00 HL125805NHLBI NIH HHS R01 HL122494NHLBI NIH HHS R01 HL136595NHLBI NIH HHS R01 HL145028
Abstract
Blood pressure is controlled by endocrine, autonomic, and behavioral responses that maintain blood volume and perfusion pressure at levels optimal for survival. Although it is clear that central angiotensin type 1a receptors (AT1aR; encoded by the
Indexed as
AngiotensinsAnimalsArginine VasopressinBasal Nucleus of MeynertBlood PressureDrinkingGenes, fosGlutamic AcidHypothalamusMaleMiceMice, Inbred C57BLMice, KnockoutNeural PathwaysOptogeneticsParaventricular Hypothalamic NucleusAgtr1a protein, mouseAngiotensinsArginine VasopressinGlutamic AcidReceptor, Angiotensin, Type 1Receptors, VasopressinSodium, DietaryVasoconstrictor Agentsangiotensin Type 1 receptorsblood pressurehypertensionmedian preoptic nucleusrenin-angiotensin system
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.