ArticleProceedings of the National Academy of Sciences of the United States of America2020
Synaptic plasticity rules with physiological calcium levels.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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60 citing papers in PubMed, 127 citations in OpenAlex.
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- Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The calcium-binding protein S100β regulates synaptic plasticity in the visual cortex.iScience · 2026Article
- Dendritic heterosynaptic plasticity arises from calcium-based input learning.Communications biology · 2026Article
- Mechanistic explanation of neuroplasticity using equivalent circuits.Frontiers in computational neuroscience · 2026Article
- Studying Synchronization of Neural Oscillators through NMDA-AMPA Receptor interactions.Chaos, solitons, and fractals · 2026Article
- Behavioral Timescale Synaptic Plasticity: A Burst in the Field of Learning and Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Automatic design and optimization of MRI-based neurochemical sensors via reinforcement learning.Discover nano · 2025Article
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- A generalized mathematical framework for the calcium control hypothesis describes weight-dependent synaptic plasticity.Journal of computational neuroscience · 2025Article
- Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells.Communications biology · 2025Article
- Synaptic plasticity rules driving representational shifting in the hippocampus.Nature neuroscience · 2025Article
- mPFC DCC coupling with CaMKIITranslational psychiatry · 2025Article
- Dendritic excitations govern back-propagation via a spike-rate accelerometer.Nature communications · 2025Article
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- Spike-timing-dependent plasticity offers delay-gated oscillatory potentiation for autaptic weights.Frontiers in neural circuits · 2025Article
- Postsynaptic spiking determines anti-Hebbian LTD in visual cortex basket cells.Frontiers in synaptic neuroscience · 2025Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Spike-timing-dependent plasticity (STDP) is considered as a primary mechanism underlying formation of new memories during learning. Despite the growing interest in activity-dependent plasticity, it is still unclear whether synaptic plasticity rules inferred from in vitro experiments are correct in physiological conditions. The abnormally high calcium concentration used in in vitro studies of STDP suggests that in vivo plasticity rules may differ significantly from in vitro experiments, especially since STDP depends strongly on calcium for induction. We therefore studied here the influence of extracellular calcium on synaptic plasticity. Using a combination of experimental (patch-clamp recording and Ca
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