Evidence map›Paper›PMID 33328202›Full record

SynthesisBMJ global health2020

Boys are more likely to be undernourished than girls: a systematic review and meta-analysis of sex differences in undernutrition.

Susan Thurstans, Charles Opondo, Andrew Seal, Jonathan Wells, Tanya Khara, Carmel Dolan, André Briend, Mark Myatt, Michel Garenne, Rebecca Sear and 1 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed, 11 pooled it
15.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 11 syntheses or guidelines pooled it, 266 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Early-life famine exposure and risk of osteoporosis and low bone mineral density: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Diarrhea as a Disease of Poverty Among Under-Five Children in Sub-Saharan Africa: A Cross-Sectional Study.Inquiry : a journal of medical care organization, provision and financing
    Pooled it
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Article
  18. Article
  19. Article
  20. Article

103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 4 countries.

Susan ThurstansDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK susan.thurstans@lshtm.ac.uk.ORCID 0000-0002-7102-446X
Charles OpondoDepartment of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0001-8155-4117
Andrew SealInstitute for Global Health, University College London, London, UK.ORCID 0000-0003-3656-4054
Jonathan WellsGreat Ormond Street Institute of Child Health, University College London, London, UK.ORCID 0000-0003-0411-8025
Tanya KharaEmergency Nutrition Network, Kidlington, Oxfordshire, UK.
Carmel DolanEmergency Nutrition Network, Kidlington, Oxfordshire, UK.
André BriendDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Kobenhavn, Denmark.
Mark MyattBrixton Health, Llwyngwril, Gwynedd, UK.
Michel GarenneInstitut de Recherche pour le Développement, UMI Résiliences, Bondy, France.ORCID 0000-0001-6073-7803
Rebecca SearDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-4315-0223
Marko KeracDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-3745-7317
London School of Hygiene & Tropical Medicine · GBGreat Ormond Street Hospital · GBGwynedd Council · GBInstitut Pasteur · FRUniversity College London · GBUniversity of Copenhagen · DKUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcess male morbidity and mortality is well recognised in neonatal medicine and infant health. In contrast, within global nutrition, it is commonly assumed that girls are more at risk of experiencing undernutrition. We aimed to explore evidence for any male/female differences in child undernutrition using anthropometric case definitions and the reasons for differences observed.

methodsWe searched: Medline, Embase, Global health, Popline and Cochrane databases with no time limits applied. Eligible studies focused on children aged 0-59 months affected by undernutrition where sex was reported. In the meta-analysis, undernutrition-specific estimates were examined separately for wasting, stunting and underweight using a random-effects model.

results74 studies were identified: 44/74 studies were included in the meta-analysis. In 20 which examined wasting, boys had higher odds of being wasted than girls (pooled OR 1.26, 95% CI 1.13 to 1.40). 38 examined stunting: boys had higher odds of stunting than girls (pooled OR 1.29 95% CI 1.22 to 1.37). 23 explored underweight: boys had higher odds of being underweight than girls (pooled OR 1.14, 95% CI 1.02 to 1.26). There was some limited evidence that the female advantage, indicated by a lower risk of stunting and underweight, was weaker in South Asia than other parts of the world. 43/74 (58%) studies discussed possible reasons for boy/girl differences; 10/74 (14%) cited studies with similar findings with no further discussion; 21/74 (28%) had no sex difference discussion. 6/43 studies (14%) postulated biological causes, 21/43 (49%) social causes and 16/43 (37%) to a combination.

conclusionOur review indicates that undernutrition in children under 5 is more likely to affect boys than girls, though the magnitude of these differences varies and is more pronounced in some contexts than others. Future research should further explore reasons for these differences and implications for nutrition policy and practice.

Indexed as

Child Nutrition DisordersMalnutritionWasting SyndromeChildFemaleGrowth DisordersHumansInfantInfant, NewbornMaleSex Characteristicschild healthnutritionpublic healthsystematic review

Identifiers

PMID33328202
PMCPMC7745319
OpenAlexW3111661446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.