Evidence map›Paper›PMID 33328064›Full record

ReviewAdvances in chronic kidney disease2020

End-Stage Kidney Disease and Dialysis in Pregnancy.

Andrea L Oliverio, Michelle A Hladunewich

Open access · greenAbstract readReview
In one paragraph

Review in Advances in chronic kidney disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Guideline
  2. Impact of maternal health on neonatal and long-term kidney outcomes.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  3. Dialysis and Pregnancy: Optimizing Therapy for Best Maternal and Fetal Outcomes.Hemodialysis international. International Symposium on Home Hemodialysis · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Kidney disease and reproductive health.Nature reviews. Nephrology · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Anemia in Pregnancy With CKD.Kidney international reports · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Management of Pregnancy in Persons with Kidney Failure Treated with Hemodialysis.Clinical journal of the American Society of Nephrology : CJASN · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Andrea L OliverioDivision of Nephrology, University of Michigan Medical School, Ann Arbor, MI. Electronic address: aoliv@med.umich.edu.
Michelle A HladunewichDivisions of Nephrology and Obstetrics, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada.
Sunnybrook Health Science Centre · CAUniversity of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Institutional Career Development CoreKL2TR002241 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELLINGROD, VICKI L · 2017 to 2021
$6.9M
NCATS NIH HHS KL2 TR002241NCATS NIH HHS UL1 TR002240
6 · The paper itself

Abstract

End-stage kidney disease is associated with low fertility, with rates of conception in women on dialysis estimated at 1/100th of the general population. However, live birth rates are increasing over time in women on hemodialysis, whereas they remain lower and static in women on peritoneal dialysis. Intensification of hemodialysis, targeting a serum blood urea nitrogen <35 mg/dL or 36 hours of dialysis per week in women with no residual kidney function, is associated with improved live birth rates and longer gestational age. Even in intensively dialyzed cohorts, rates of prematurity and need for neonatal intensive care are high, upwards of 50%. Although women on peritoneal dialysis in pregnancy do not appear to be at increased risk of delivering preterm compared with those on hemodialysis, their infants are more likely to be small for gestational age. As such, hemodialysis has emerged as the preferred dialysis modality in pregnancy. Provision of specialized nephrology, obstetric, and neonatal care is necessary to manage these complex pregnancies and family planning counseling should be offered to all women with end-stage kidney disease.

Indexed as

Kidney Failure, ChronicPregnancy ComplicationsRenal DialysisFemaleHumansPregnancyPregnancy, High-RiskPregnancy OutcomeRisk AdjustmentDialysisESKDFetalObstetricsPregnancy

Identifiers

PMID33328064
PMCPMC7781109
OpenAlexW3112669448

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.