Evidence map›Paper›PMID 33327936›Full record

Trial reportJournal of neurodevelopmental disorders2020

Psychosocial deprivation and receptive language ability: a two-sample study.

Kathryn L Humphreys, Laura S Machlin, Katherine L Guyon-Harris, Charles A Nelson, Nathan A Fox, Charles H Zeanah

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neurodevelopmental disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00747396 (The Bucharest Early Intervention Project), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00747396 naactive not recruitingnot on this map

The Bucharest Early Intervention Project: Effects of Early Psychosocial Deprivation on Mental Health in Adolescence

TypeinterventionalSponsorCharles Alexander Nelson IIIRan2000 to 2027Enrolled136ConditionsCognitive Ability, General, Psychiatric and/or Mood Disorders, Brain Function, Social CognitionArmsFoster Care Placement
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Working memory related brain-behavior associations in the context of socioeconomic and psychosocial deprivation.Cortex; a journal devoted to the study of the nervous system and behavior · 2024
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kathryn L HumphreysVanderbilt University, Nashville, TN, 37203, USA. k.humphreys@vanderbilt.edu.ORCID 0000-0002-5715-6597
Laura S MachlinUniversity of North Carolina, Chapel Hill, Chapel Hill, USA.
Katherine L Guyon-HarrisUniversity of Pittsburgh School of Medicine, Pittsburgh, USA.
Charles A NelsonBoston Children's Hospital/Harvard Medical School, Boston, USA.
Nathan A FoxUniversity of Maryland, College Park, USA.
Charles H ZeanahTulane University School of Medicine, New Orleans, USA.

Funding

The Relation Between Early Psychosocial Deprivation and Mental Health at 12 YearsR01MH091363 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI FOX, NATHAN A, NELSON, CHARLES ALEXANDER · 2010 to 2024
$9.2M
Human Development: Interdisiplinary Research TrainingT32HD007376 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BELGER, AYSENIL, PROPPER, CATHI BARBRA · 1988 to 2020
$8.0M
Future of Families and Child Wellbeing Study Summer Data WorkshopR25HD074544 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Amanda Geller, Julien O Teitler · 2013 to 2026
$1.5M
HRSA HHS T32HP22240Jacobs Foundation 2017-1261-05National Institute of Child Health and Human Development T32HD07376NICHD NIH HHS R25 HD074544NICHD NIH HHS T32 HD007376NIMH NIH HHS MH091363NIMH NIH HHS R01 MH091363
6 · The paper itself

Abstract

backgroundThe quality of early caregiving experiences is a known contributor to the quality of the language experiences young children receive. What is unknown is whether, and if so, how psychosocial deprivation early in life is associated with long-lasting receptive language outcomes.

methodsTwo prospective longitudinal studies examining early psychosocial deprivation/neglect in different contexts (i.e., deprivation due to institutional care or deprivation experienced by children residing within US families) and receptive language as assessed via the Peabody Picture Vocabulary Test (PPVT) were used to assess the magnitude of these associations. First, 129 participants from the Bucharest Early Intervention Project, a randomized controlled trial of foster care as an alternative to institutional care in Romania, completed a receptive language assessment at age 18 years. Second, from the USA, 3342 participants from the Fragile Families and Child Wellbeing Study were assessed from infancy until middle childhood.

resultsChildren exposed to early institutional care, on average, had lower receptive language scores than their never institutionalized counterparts in late adolescence. While randomization to an early foster care intervention had no long-lasting association with PPVT scores, the duration of childhood exposure to institutional care was negatively associated with receptive language. Psychosocial deprivation in US families was also negatively associated with receptive language longitudinally, and this association remained statistically significant even after accounting for measures of socioeconomic status.

conclusionExperiences of psychosocial deprivation may have long-lasting consequences for receptive language ability, extending to age 18 years. Psychosocial deprivation is an important prospective predictor of poorer receptive language.

trial registrationBucharest Early Intervention Project ClinicalTrials.gov Identifier: NCT00747396.

Indexed as

LanguagePsychosocial DeprivationAdolescentChildChild, PreschoolFoster Home CareHumansLanguage DevelopmentProspective StudiesRomaniaDeprivationNeglectReceptive languageSocioeconomic status

Identifiers

PMID33327936
PMCPMC7745465

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.