Evidence map›Paper›PMID 33327874›Full record

ArticleTechnology in cancer research & treatment

miR-146b Functions as an Oncogene in Oral Squamous Cell Carcinoma by Targeting HBP1.

Kui Li, Zheng Zhou, Ju Li, Rui Xiang

Open access · goldAbstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Kui LiDepartment of Stomatology, Guangyuan Central Hospital, Guangyuan, Sichuan Province, China.
Zheng ZhouDepartment of stomatology, Xiangyang Stomatological Hospital, Xiangyang City, Hubei Province, China.
Ju LiDepartment of stomatology, First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan Province, China.
Rui XiangDepartment of prosthodontics, WuXi Stomatology Hospital, Jiangsu Province, China.ORCID 0000-0001-9242-6137
Deyang Stomatological Hospital · CNFirst Affiliated Hospital of Chengdu Medical College · CNStomatology Hospital · CNTaiyuan Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) represents more than 90% of all oral cancer and is the most common oral threat around the world. In this study, we examined the roles of miR-146b in OSCC cells. The miR-146b expression in OSCC tissues and cell lines was evaluated by quantitative real-time PCR (qRT-PCR). MTT assay was used to investigate the impact of miR-146b on the growth of OSCC cells

Indexed as

Cell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticGene Knockout TechniquesHigh Mobility Group ProteinsHumansMicroRNAsMouth NeoplasmsNeoplasm InvasivenessRepressor ProteinsSquamous Cell Carcinoma of Head and NeckHBP1 protein, humanHigh Mobility Group ProteinsMicroRNAsMIRN146 microRNA, humanRepressor ProteinsHBP1miR-146bMTTOSCCqRT-PCR

Identifiers

PMID33327874
PMCPMC7750896
OpenAlexW3113089339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.