Evidence map›Paper›PMID 33327851›Full record

ArticleJournal of the International Association of Providers of AIDS Care

Perceptions of Long-Acting Injectable Antiretroviral Treatment Regimens in a United States Urban Academic Medical Center.

David E Koren, Volodymyra Fedkiv, Huaqing Zhao, Geena Kludjian, Robert L Bettiker, Ellen Tedaldi, Rafik Samuel

Abstract read
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David E KorenDepartment of Pharmacy Services, Temple University Hospital, Philadelphia, PA, USA.ORCID 0000-0002-6601-9893
Volodymyra FedkivDepartment of Pharmacy Services, Temple University Hospital, Philadelphia, PA, USA.
Huaqing ZhaoDepartment of Clinical Sciences, 12314Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Geena KludjianDepartment of Pharmacy Services, Temple University Hospital, Philadelphia, PA, USA.
Robert L BettikerSection of Infectious Diseases, 12314Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Ellen TedaldiSection of General Internal Medicine, 12314Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Rafik SamuelSection of Infectious Diseases, 12314Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient acceptance of long-acting injectable antiretroviral (LAI-ARV) HIV-1 regimens will determine uptake. Although previous literature reports high satisfaction, these data stem from clinical trials subject to selection bias. This cross-sectional survey from the HIV practices of an urban academic medical center assessed perceptions and preferences using Likert scales toward overall acceptability, proposed frequencies, injection-site reaction durations, and distribution venue. 59% of surveys were completed resulting 202 respondents. 60% were male, 72% black, and the median age was 49 (IQR 36-58). 93% reported a once daily tablet frequency, 69% reported single tablet regimens, and 59% reported missing zero doses in the prior 30 days. Patients self-categorized as likely (57%) or unlikely (43%) to accept LAI-ARV. Both decreasing frequencies between injections and durations of injection-site reactions resulted higher acceptability scores. 57% of respondents preferred receiving an injectable from their clinician's office over other potential options. These data demonstrate positive LAI-ARV acceptance potential.

Indexed as

Academic Medical CentersAdultAnti-Retroviral AgentsCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMiddle AgedOutcome Assessment, Health CarePatient Acceptance of Health CarePatient PreferencePerceptionUnited StatesAnti-Retroviral Agentsantiretroviral treatmentHIVinjectableperceptions

Identifiers

PMID33327851
PMCPMC7750752

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.