Evidence map›Paper›PMID 33327813›Full record

ArticleThe Journal of international medical research2020

Combining real-time elastography with fine-needle aspiration biopsy to identify malignant thyroid nodules.

Lei Zhu, Yanyan Chen, Huijun Ai, Wei Gong, Bin Zhou, Yonghong Xu, Shuzheng Chen, Feng Cheng

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 58 citations in OpenAlex.

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  14. Of sight, and insight into melatonin's role in breast cancer?Revista da Associacao Medica Brasileira (1992) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lei ZhuDepartment of Thyroid and Breast Surgery, Lishui Municipal Central Hospital, Lishui Hospital of Zhejiang University, Lishui, China.
Yanyan ChenDepartment of Surgical Oncology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou China.
Huijun AiDepartment of Ultrasound, Lishui Municipal Central Hospital, Lishui Hospital of Zhejiang University, Lishui China.
Wei GongDepartment of Pathology, Lishui Municipal Central Hospital, Lishui Hospital of Zhejiang University, Lishui, China.
Bin ZhouDepartment of Thyroid and Breast Surgery, Lishui Municipal Central Hospital, Lishui Hospital of Zhejiang University, Lishui, China.
Yonghong XuDepartment of Thyroid and Breast Surgery, Lishui Municipal Central Hospital, Lishui Hospital of Zhejiang University, Lishui, China.
Shuzheng ChenDepartment of Thyroid and Breast Surgery, Lishui Municipal Central Hospital, Lishui Hospital of Zhejiang University, Lishui, China.
Feng ChengDepartment of Thyroid and Breast Surgery, Lishui Municipal Central Hospital, Lishui Hospital of Zhejiang University, Lishui, China.ORCID https://orcid.org/0000-0002-1977-9910
Lishui Central Hospital · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the diagnostic performance of real-time elastography (RTE) combined with fine-needle aspiration (FNA) biopsy in identifying malignant thyroid nodules.

methodsThis was a single-centre, retrospective study and involved patients who had underogone partial or total thyroidectomy from 01 January 2014 to 31 December 2018 at our centre. Eligible patients were at least18 years of age, had reliable grayscale ultrasound imaging results, a RTE evaluation and had undergone a FNA biopsy.

resultsData were available from 437 patients. A high RTE score was a significant independent risk factors for malignancy. RTE plus FNA biopsy increased diagnostic accuracy compared with either method alone and the sensitivity and specificity of the combined model were 86% and 78%, respectively.

conclusionsThe combination of RTE imaging with FNA biopsy improves the diagnostic performance in differentiating benign and malignant thyroid nodules.

Indexed as

Elasticity Imaging TechniquesThyroid NeoplasmsThyroid NoduleBiopsy, Fine-NeedleFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityUltrasonographydiagnostic accuracyfine-needle aspiration biopsygrayscale ultrasoundreal-time elastographyThyroid nodule

Identifiers

PMID33327813
PMCPMC7747118
OpenAlexW3111813950

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.