Evidence map›Paper›PMID 33327646›Full record

ReviewDiagnostics (Basel, Switzerland)2020

Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis.

Constantina Aggeli, Yannis Dimitroglou, Leonidas Raftopoulos, Georgia Sarri, Sophie Mavrogeni, Joyce Wong, Eleftherios Tsiamis, Costas Tsioufis

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A rare giant asymptomatic biatrial myxoma.Journal of cardiothoracic surgery · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Advancing cardiac tumor diagnosis: evaluatingAmerican journal of cardiovascular disease · 2026
    Review
  7. Article
  8. Article
  9. An uncommon case of a rapidly growing intracardiac mass.Global cardiology science & practice · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Primary cardiac angiosarcoma - a diagnostic roller-coaster till fatality.Journal of cardiovascular and thoracic research · 2025
    Article
  16. Article
  17. Cardiac myxoma: a comprehensive review.Journal of cardiothoracic surgery · 2025
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Constantina AggeliFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, Greece.
Yannis DimitroglouFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, Greece.ORCID 0000-0001-7340-5242
Leonidas RaftopoulosFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, Greece.
Georgia SarriFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, Greece.
Sophie MavrogeniDepartment of Cardiology, Onassis Cardiac Surgery Centre, 17674 Kallithea, Attica, Greece.
Joyce WongDepartment of Cardiology, Harefield Hospital, Royal Brompton Hospital, London UB96JH, UK.
Eleftherios TsiamisFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, Greece.
Costas TsioufisFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac masses are space occupying lesions within the cardiac cavities or adjacent to the pericardium. They include frequently diagnosed clinical entities such as clots and vegetations, common benign tumors such as myxomas and papillary fibroelastomas and uncommon benign or malignant primary or metastatic tumors. Given their diversity, there are no guidelines or consensus statements regarding the best diagnostic or therapeutic approach. In the past, diagnosis used to be made by the histological specimens after surgery or during the post-mortem examination. Nevertheless, evolution and increased availability of cardiovascular imaging modalities has enabled better characterization of the masses and the surrounding tissue. Transthoracic echocardiography using contrast agents can evaluate the location, the morphology and the perfusion of the mass as well as its hemodynamic effect. Transesophageal echocardiography has increased spatial and temporal resolution; hence it is superior in depicting small highly mobile masses. Cardiac magnetic resonance and cardiac computed tomography are complementary providing tissue characterization. The scope of this review is to present the role of cardiovascular imaging in the differential diagnosis of cardiac masses and to propose a step-wise diagnostic algorithm, taking into account the epidemiology and clinical presentation of the cardiac masses, as well as the availability and the incremental value of each imaging modality.

Indexed as

cardiac computed tomographycardiac magnetic resonancecardiac malignanciescardiac tumorscontrast agentsechocardiographytransesophageal echocardiography

Identifiers

PMID33327646
PMCPMC7765127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.