Evidence map›Paper›PMID 33327636›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Associations between Coenzyme Q10 Status, Oxidative Stress, and Muscle Strength and Endurance in Patients with Osteoarthritis.

Po-Sheng Chang, Chi-Hua Yen, Yu-Yun Huang, Ching-Ju Chiu, Ping-Ting Lin

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Unlocking Parkinson's disease: the role of microRNAs in regulation, diagnosis, and therapy.Apoptosis : an international journal on programmed cell death · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Levels of Plasma Coenzyme QAntioxidants (Basel, Switzerland) · 2022
    Article
  16. Oral administration of live combinedFrontiers in microbiology · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Po-Sheng ChangDepartment of Nutrition, Chung Shan Medical University, Taichung 402367, Taiwan.
Chi-Hua YenSchool of Medicine, Chung Shan Medical University, Taichung 402367, Taiwan.
Yu-Yun HuangDepartment of Nutrition, Chung Shan Medical University, Taichung 402367, Taiwan.
Ching-Ju ChiuDepartment of Nutrition, Chung Shan Medical University, Taichung 402367, Taiwan.
Ping-Ting LinDepartment of Nutrition, Chung Shan Medical University, Taichung 402367, Taiwan.ORCID 0000-0002-4271-3928
Chung Shan Medical University · TWChung Shan Medical University Hospital · TW

Funding

Ministry of Science and Technology, Taiwan MOST 107-2320-B-040-011
6 · The paper itself

Abstract

Osteoarthritis (OA) causes oxidative stress. Coenzyme Q10 is an antioxidant that participates in energy production in the human body. The purpose of this study was to investigate the relationships among coenzyme Q10 status, oxidative stress, antioxidant capacity, and muscle function in patients with OA. This case-control study recruited 100 patients with OA and 100 without OA. The coenzyme Q10 status, oxidative stress, antioxidant capacity, muscle mass (by dual-energy X-ray absorptiometry), muscle strength (hand-grip and leg-back strength), and muscle endurance (dumbbell curls, gait speed, chair-stand test, and short physical performance battery) were measured. The results showed that both OA and elderly subjects had a low coenzyme Q10 status (<0.5 μM). Oxidative stress was significantly negatively correlated with muscle function (protein carbonyl,

Indexed as

agingcoenzyme Q10muscle functionmuscle massosteoarthritisoxidative stress

Identifiers

PMID33327636
PMCPMC7765116
OpenAlexW3111571119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.