Evidence map›Paper›PMID 33327563›Full record

ArticleCancers2020

Multidisciplinary Management of Radiation-Induced Salivary Gland Carcinomas in the Modern Radiotherapy Era.

Domenico Attilio Romanello, Zulfiyya Imamguliyeva, Stefano Cavalieri, Barbara Vischioni, Lorenza Gandola, Alberto Iannalfi, Nicola Alessandro Iacovelli, Lisa Licitra, Marco Guzzo, Cesare Piazza and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. International journal of particle therapy · 2025
    Review
  2. Frontiers in oncology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Domenico Attilio RomanelloRadiotherapy Unit, National Center of Oncological Hadrontherapy (CNAO), 27100 Pavia, Italy.
Zulfiyya ImamguliyevaDepartment of Head and Neck Tumors, National Center of Oncology, Baku AZ1012, Azerbaijan.ORCID 0000-0002-4603-4519
Stefano CavalieriHead and Neck Cancer Medical Oncology 3 Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy.ORCID 0000-0003-1294-6859
Barbara VischioniRadiotherapy Unit, National Center of Oncological Hadrontherapy (CNAO), 27100 Pavia, Italy.
Lorenza GandolaRadiotherapy 1 Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Alberto IannalfiRadiotherapy Unit, National Center of Oncological Hadrontherapy (CNAO), 27100 Pavia, Italy.
Nicola Alessandro IacovelliRadiotherapy 1-2 Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Lisa LicitraHead and Neck Cancer Medical Oncology 3 Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy.
Marco GuzzoDepartment of Otorhinolaryngology, Maxillofacial, and Thyroid Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Cesare PiazzaUnit of Otorhinolaryngology-Head and Neck Surgery, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, 25123 Brescia, Italy.
Davide LombardiUnit of Otorhinolaryngology-Head and Neck Surgery, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0001-8430-4789
Barbara DilettoRadiotherapy 1-2 Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Pasquale QuattronePathology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy.
Giuseppina CalaresoDepartment of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy.
Laura Deborah LocatiHead and Neck Cancer Medical Oncology 3 Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy.
Ester OrlandiRadiotherapy Unit, National Center of Oncological Hadrontherapy (CNAO), 27100 Pavia, Italy.
Fondazione IRCCS Istituto Nazionale dei Tumori · ITNational Center for Oncological Hadrontherapy · ITUniversity of Brescia · ITUniversity of Milan · ITVA Fanarjian National Center of Oncology · AZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical data of ri-SGCs patients treated between 2015 and 2019 at a tertiary cancer center and a national hadron therapy facility were reviewed. Latent time (LT) from first RT to ri-SGCs diagnosis, overall (OS), and disease-free survival (DFS) were assessed. Thirteen patients developed 14 ri-SGCs (one patient had 2 synchronous ri-SCGs), after a median LT of 23 years (range 16-34). Parotid was the primary site in 8 cases (57%) and salivary duct carcinoma was the most frequent histotype (29%). Nine patients (69%) underwent surgery (Sx). Among them, 4 patients (31%) underwent Sx alone, 5 received post-operative treatments: 3 (23%) photon-based (X) reRT, one (8%) protons and carbon ions, one (8%) carbon ions only. One patient (8%) received definitive XRT. The remaining 3 patients (23%) received androgen deprivation therapy. With a median follow-up of 48 months (range 24-72), median OS and PFS were 74 and 24 months, respectively. In the subgroup of AR

Indexed as

hormone therapymultidisciplinary managementparticle therapyRadiation induced cancerradiotherapysalivary gland cancersurgery

Identifiers

PMID33327563
PMCPMC7765068
OpenAlexW3110779668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.