Evidence map›Paper›PMID 33327519›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Modified Bacterial Cellulose Dressings to Treat Inflammatory Wounds.

Uwe Beekmann, Paul Zahel, Berit Karl, Lisa Schmölz, Friedemann Börner, Jana Gerstmeier, Oliver Werz, Stefan Lorkowski, Cornelia Wiegand, Dagmar Fischer and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Uwe BeekmannPharmaceutical Technology and Biopharmacy, Institute of Pharmacy, Friedrich Schiller University, Lessingstraße 8, 07743 Jena, Germany.ORCID 0000-0002-9839-5527
Paul ZahelPharmaceutical Technology and Biopharmacy, Institute of Pharmacy, Friedrich Schiller University, Lessingstraße 8, 07743 Jena, Germany.ORCID 0000-0002-0455-6044
Berit KarlPharmaceutical Technology and Biopharmacy, Institute of Pharmacy, Friedrich Schiller University, Lessingstraße 8, 07743 Jena, Germany.
Lisa SchmölzNutritional Biochemistry and Physiology, Institute of Nutritional Sciences, Friedrich Schiller University, Dornburger Straße 25, 07743 Jena, Germany.
Friedemann BörnerPharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Philosophenweg 14, 07743 Jena, Germany.
Jana GerstmeierPharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Philosophenweg 14, 07743 Jena, Germany.
Oliver WerzPharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Philosophenweg 14, 07743 Jena, Germany.ORCID 0000-0002-5064-4379
Stefan LorkowskiNutritional Biochemistry and Physiology, Institute of Nutritional Sciences, Friedrich Schiller University, Dornburger Straße 25, 07743 Jena, Germany.ORCID 0000-0002-9649-840X
Cornelia WiegandDepartment of Dermatology, Jena University Hospital, Erfurter Str. 35, 07743 Jena, Germany.
Dagmar FischerPharmaceutical Technology and Biopharmacy, Institute of Pharmacy, Friedrich Schiller University, Lessingstraße 8, 07743 Jena, Germany.
Dana KralischPharmaceutical Technology and Biopharmacy, Institute of Pharmacy, Friedrich Schiller University, Lessingstraße 8, 07743 Jena, Germany.
Friedrich Schiller University Jena · DEJena University Hospital · DE

Funding

Deutsche Forschungsgemeinschaft Collaborative Research Center SFB 1278 PolyTarget, project number 316213987European Social Fund 2016 FGR 0045
6 · The paper itself

Abstract

Natural products suited for prophylaxis and therapy of inflammatory diseases have gained increasing importance. These compounds could be beneficially integrated into bacterial cellulose (BC), which is a natural hydropolymer applicable as a wound dressing and drug delivery system alike. This study presents experimental outcomes for a natural anti-inflammatory product concept of boswellic acids from frankincense formulated in BC. Using esterification respectively (resp.) oxidation and subsequent coupling with phenylalanine and tryptophan,

Indexed as

anti-inflammatorybacterial celluloseboswellic aciddiclofenacdrug delivery systemindomethacinwound dressing

Identifiers

PMID33327519
PMCPMC7764978
OpenAlexW3111718759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.