Evidence map›Paper›PMID 33327321›Full record

ArticleMedicine2020

Primary multiple angiosarcoma of vertebra: A case report.

Wei Huang, Tao Liu, Ruimeng Duan, Yashuai Yuan, Mingjia Qu, Meng Zhang, Depeng Shang, Xiaobing Yu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Treatments and outcomes of primary and metastatic spinal angiosarcoma patients: study of 29 consecutive cases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Article
  3. Article
  4. Angiosarcoma in the femoral bone: A case report of a rare bone tumor.International journal of surgery case reports · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Wei HuangDepartment of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, 116001, China.
Tao LiuDepartment of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, 116001, China.
Ruimeng DuanDepartment of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, 116001, China.
Yashuai YuanDepartment of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, 116001, China.
Mingjia QuDepartment of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, 116001, China.
Meng ZhangDepartment of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, 116001, China.
Depeng ShangDepartment of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, 116001, China.
Xiaobing YuDepartment of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, 116001, China.ORCID 0000-0002-6559-2938
Affiliated Zhongshan Hospital of Dalian University · CNTung Wah Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleAngiosarcoma is a rare malignant tumors. The objective of this study is to report a patient who suffered from a progressive low back pain and left lower extremities radiation pain for about 8 months, After diagnoses, this was identified as an extremely rare case of primary multiple angiosarcoma of vertebra. PATIENT CONCERNS: A 54-year-old man with a history of 2-year hypertension and 8-year diabetes, both of which were well controlled by drug management. Lately, he suffered from a progressive low back pain and left lower extremities radiation pain for about 8 months. DIAGNOSES: Magnetic resonance imaging of lumbar showed a clear pathological fracture and primary multiple angiosarcoma of all vertebra. Postoperative pathology and High-throughput sequencing confirmed the diagnosis of primary multiple angiosarcoma of vertebra.

interventionsThe patient underwent minimally invasive pedicle screw fixation combined with bone cement augmentation for the purpose of stabilizing the damaged vertebrae. Following operation, he received both radiotherapy and chemotherapy for a period of time. OUTCOMES: The operation has achieved positive results in relieving pain and stabilizing the spine. No wound problem or operative complications occurred after operation. The patient reported an obvious remission of low back pain and was only capable to perform restricted physiological activities. A long-term palliative radiotherapy and chemotherapy were performed after operation. Unfortunately, the patient died 18 months later.

conclusionThis article emphasizes primary multiple angiosarcoma of vertebra. Despite being rare, it should be part of the differential when the patient manifested back pain and radiculopathy. We recommended the minimally invasive pedicle screw fixation for angiosarcoma of vertebra. Osteoplasty by bone cement augmentation was also an ideal choice for surgical treatment. It also advocates the use of specific targeted radiotherapy drugs based on gene analysis of tumors.

Indexed as

Lumbar VertebraeCombined Modality TherapyFractures, SpontaneousHemangiosarcomaHumansLow Back PainMagnetic Resonance ImagingMaleMiddle AgedNeoplasms, Multiple PrimaryPedicle ScrewsSpinal Neoplasms

Identifiers

PMID33327321
PMCPMC7738032
OpenAlexW3111138935

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.