Evidence map›Paper›PMID 33326761›Full record

ArticleImmunity2020

Resolving the Instructions for αβ T Cell Development.

Sarah B Cleveland, Eric S Huseby

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. T Cell Development: From T-Lineage Specification to Intrathymic Maturation.Advances in experimental medicine and biology · 2025
    Review
  2. Rediscovering the human thymus through cutting-edge technologies.The Journal of experimental medicine · 2024
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sarah B ClevelandDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Eric S HusebyDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA. Electronic address: eric.huseby@umassmed.edu.
University of Massachusetts Chan Medical School · US

Funding

TRAINING IN IMMUNOLOGY (COMPETITIVE RENEWAL OF AI07439)T32AI007349 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STERN, LAWRENCE J. · 1989 to 2024
$4.5M
TCR signaling control of thymic Treg selection and immune homeostasisR01AI143976 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BERG, LESLIE JOAN, HUSEBY, ERIC S · 2020 to 2024
$2.9M
Interplay of Regulatory Innate T Cells and Pathogenic T Clonotypes In DermatitisR01AR071269 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HUSEBY, ERIC S, KANG, JOONSOO · 2017 to 2021
$2.9M
IMSD at the University of Massachusetts Medical SchoolT32GM135751 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BRIAN C LEWIS, Kate L Lapane · 2020 to 2026
$2.2M
NIAID NIH HHS R01 AI143976NIAID NIH HHS T32 AI007349NIAMS NIH HHS R01 AR071269NIGMS NIH HHS T32 GM135751
6 · The paper itself

Abstract

In this issue of Immunity, Chopp et. al. use single-cell transcriptomics and epigenomics in mice and human samples to delineate developmental trajectories of αβ T cell subsets and refine the kinetic selection model of CD4

Indexed as

Receptors, Antigen, T-Cell, alpha-betaReceptors, Antigen, T-Cell, gamma-deltaAnimalsCell DifferentiationEpigenomicsHumansMiceT-Lymphocyte SubsetsTranscriptomeReceptors, Antigen, T-Cell, alpha-betaReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID33326761
PMCPMC8530263
OpenAlexW3111511008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.