ArticlePloS one2020
Outcomes of an intermediate respiratory care unit in the COVID-19 pandemic.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Intubation rate of patients with hypoxia due to COVID-19 treated with awake proning: A meta-analysis.The American journal of emergency medicine · 2021Pooled it
- Prone Positioning in Patients With COVID-19: Analysis of Multicenter Registry Data and Meta-analysis of Aggregate Data.In vivo (Athens, Greece)Pooled it
- Innovations and Challenges in Intermediate Respiratory Care Units: Toward Effective Integration into the Hospital System.Open respiratory archives · 2024Review
- A randomised clinical trial of awake prone positioning in COVID-19 suspects with acute hypoxemic respiratory failure.Contemporary clinical trials communications · 2024Article
- What Is the Place of Intermediate Care Unit in Patients with COVID-19? A Single Center Experience.International journal of clinical practice · 2023Article
- Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research.The Lancet. Respiratory medicine · 2022Review
- The Role of Noninvasive Respiratory Management in Patients with Severe COVID-19 Pneumonia.Journal of personalized medicine · 2021Review
- One year on: Are we ready for COVID?Archivos de bronconeumologia · 2021Article
- Role of respiratory intermediate care units during the SARS-CoV-2 pandemic.BMC pulmonary medicine · 2021Article
- Collaborative and Structured Network for Maintenance of Mechanical Ventilators during the SARS-CoV-2 Pandemic.Healthcare (Basel, Switzerland) · 2021Article
- One Year On: Are We Ready for COVID?Archivos de bronconeumologia · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background15% of COVID-19 patients develop severe pneumonia. Non-invasive mechanical ventilation and high-flow nasal cannula can reduce the rate of endotracheal intubation in adult respiratory distress syndrome, although failure rate is high.
objectiveTo describe the rate of endotracheal intubation, the effectiveness of treatment, complications and mortality in patients with severe respiratory failure due to COVID-19.
methodsProspective cohort study in a first-level hospital in Madrid. Patients with a positive polymerase chain reaction for SARS-CoV-2 and admitted to the Intermediate Respiratory Care Unit with tachypnea, use of accessory musculature or SpO2 <92% despite FiO2> 0.5 were included. Intubation rate, medical complications, and 28-day mortality were recorded. Statistical analysis through association studies, logistic and Cox regression models and survival analysis was performed.
resultsSeventy patients were included. 37.1% required endotracheal intubation, 58.6% suffered medical complications and 24.3% died. Prone positioning was independently associated with lower need for endotracheal intubation (OR 0.05; 95% CI 0.005 to 0.54, p = 0.001). The adjusted HR for death at 28 days in the group of patients requiring endotracheal intubation was 5.4 (95% CI 1.51 to 19.5; p = 0.009).
conclusionsThe rate of endotracheal intubation in patients with severe respiratory failure from COVID-19 was 37.1%. Complications and mortality were lower in patients in whom endotracheal intubation could be avoided. Prone positioning could reduce the need for endotracheal intubation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.